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Dexmedetomidine alleviates pulmonary fibrosis through the ADORA2B-Mediated MAPK signaling pathway

BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a chronically progressive fibrotic pulmonary disease characterized by an uncertain etiology, a poor prognosis, and a paucity of efficacious treatment options. Dexmedetomidine (Dex), an anesthetic-sparing alpha-2 adrenoceptor (α2AR) agonist, plays a...

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Detalles Bibliográficos
Autores principales:	Lai, Xiaofan, Lin, Yingying, Huang, Shaojie, Pu, Lvya, Zeng, Qihao, Wang, Zhongxing, Huang, Wenqi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10464018/ https://www.ncbi.nlm.nih.gov/pubmed/37644529 http://dx.doi.org/10.1186/s12931-023-02513-3

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