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Desmocollin-1 is associated with pro-metastatic phenotype of luminal A breast cancer cells and is modulated by parthenolide

BACKGROUND: Desmocollin-1 (DSC1) is a desmosomal transmembrane glycoprotein that maintains cell-to-cell adhesion. DSC1 was previously associated with lymph node metastasis of luminal A breast tumors and was found to increase migration and invasion of MCF7 cells in vitro. Therefore, we focused on DSC...

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Detalles Bibliográficos
Autores principales: Lapcik, Petr, Sulc, Petr, Janacova, Lucia, Jilkova, Katerina, Potesil, David, Bouchalova, Pavla, Müller, Petr, Bouchal, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10464112/
https://www.ncbi.nlm.nih.gov/pubmed/37620794
http://dx.doi.org/10.1186/s11658-023-00481-6

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