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Development and validation of a facile rapid assessment scale for perinatal venous thromboembolism in puerperium in Chinese women

BACKGROUND: It is still urgent and challenge to develop a simple risk assessment scale for venous thromboembolism (VTE) in puerperium in Chinese women. METHODS: The study, a retrospective case-control study, was conducted in 12 hospitals in different cities in China. A total of 1152 pregnant women w...

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Autores principales: Chen, Xiujuan, Peng, Wei, Zhang, Yan, Zhou, Huansheng, Zhang, Meng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10464158/
https://www.ncbi.nlm.nih.gov/pubmed/37620792
http://dx.doi.org/10.1186/s12884-023-05901-1
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author Chen, Xiujuan
Peng, Wei
Zhang, Yan
Zhou, Huansheng
Zhang, Meng
author_facet Chen, Xiujuan
Peng, Wei
Zhang, Yan
Zhou, Huansheng
Zhang, Meng
author_sort Chen, Xiujuan
collection PubMed
description BACKGROUND: It is still urgent and challenge to develop a simple risk assessment scale for venous thromboembolism (VTE) in puerperium in Chinese women. METHODS: The study, a retrospective case-control study, was conducted in 12 hospitals in different cities in China. A total of 1152 pregnant women were selected, including 384 cases with VTE and 768 cases without VTE. A logistic regression method was conducted to determine the risk factors of VTE. RESULTS: Age, BMI before delivery, gestational diabetes mellitus, family history (thrombosis, diabetes, cardiovascular disease), and assisted reproductive technology were independent risk factors (P<0.05). The difference between the high-risk group and the low-risk group was statistically significant(P<0.001) with a sensitivity of 0.578, specificity of 0.756, Yuden index o.334, and area under the ROC curve of 0.878. CONCLUSIONS: The age (≥ 35 years), BMI before delivery (≥ 30 kg/m(2)), gestational diabetes mellitus, family history of related diseases and assisted reproductive technology are more likely to cause VTE after full-time delivery. The simple and rapid assessment scale of VTE in women after full-term delivery has perfect discrimination (P < 0.001), which can be applied to predict the risk of VTE in Chinese full-term postpartum women.
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spelling pubmed-104641582023-08-30 Development and validation of a facile rapid assessment scale for perinatal venous thromboembolism in puerperium in Chinese women Chen, Xiujuan Peng, Wei Zhang, Yan Zhou, Huansheng Zhang, Meng BMC Pregnancy Childbirth Research BACKGROUND: It is still urgent and challenge to develop a simple risk assessment scale for venous thromboembolism (VTE) in puerperium in Chinese women. METHODS: The study, a retrospective case-control study, was conducted in 12 hospitals in different cities in China. A total of 1152 pregnant women were selected, including 384 cases with VTE and 768 cases without VTE. A logistic regression method was conducted to determine the risk factors of VTE. RESULTS: Age, BMI before delivery, gestational diabetes mellitus, family history (thrombosis, diabetes, cardiovascular disease), and assisted reproductive technology were independent risk factors (P<0.05). The difference between the high-risk group and the low-risk group was statistically significant(P<0.001) with a sensitivity of 0.578, specificity of 0.756, Yuden index o.334, and area under the ROC curve of 0.878. CONCLUSIONS: The age (≥ 35 years), BMI before delivery (≥ 30 kg/m(2)), gestational diabetes mellitus, family history of related diseases and assisted reproductive technology are more likely to cause VTE after full-time delivery. The simple and rapid assessment scale of VTE in women after full-term delivery has perfect discrimination (P < 0.001), which can be applied to predict the risk of VTE in Chinese full-term postpartum women. BioMed Central 2023-08-24 /pmc/articles/PMC10464158/ /pubmed/37620792 http://dx.doi.org/10.1186/s12884-023-05901-1 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Chen, Xiujuan
Peng, Wei
Zhang, Yan
Zhou, Huansheng
Zhang, Meng
Development and validation of a facile rapid assessment scale for perinatal venous thromboembolism in puerperium in Chinese women
title Development and validation of a facile rapid assessment scale for perinatal venous thromboembolism in puerperium in Chinese women
title_full Development and validation of a facile rapid assessment scale for perinatal venous thromboembolism in puerperium in Chinese women
title_fullStr Development and validation of a facile rapid assessment scale for perinatal venous thromboembolism in puerperium in Chinese women
title_full_unstemmed Development and validation of a facile rapid assessment scale for perinatal venous thromboembolism in puerperium in Chinese women
title_short Development and validation of a facile rapid assessment scale for perinatal venous thromboembolism in puerperium in Chinese women
title_sort development and validation of a facile rapid assessment scale for perinatal venous thromboembolism in puerperium in chinese women
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10464158/
https://www.ncbi.nlm.nih.gov/pubmed/37620792
http://dx.doi.org/10.1186/s12884-023-05901-1
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