Cargando…

The impact of integrase inhibitors on steatosis and fibrosis biomarkers in persons with HIV naïve to antiretroviral therapy

BACKGROUND: Non-alcoholic Fatty Liver Disease (NAFLD) has a high prevalence among persons with HIV infection. Since Integrase Strand Transfer Inhibitors (INSTIs) are used worldwide and have been associated with weight gain, we must determine their effect in the development of NAFLD and Non-alcoholic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fernandes, Sara Rodrigues, Leite, Ana Rita, Lino, Rita, Guimarães, André Rodrigues, Pineiro, Carmela, Serrão, Rosário, Freitas, Paula
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10464196/ https://www.ncbi.nlm.nih.gov/pubmed/37620821 http://dx.doi.org/10.1186/s12879-023-08530-3

Ejemplares similares

HIV integrase variability and genetic barrier in antiretroviral naïve and experienced patients
por: Piralla, Antonio, et al.
Publicado: (2011)

HIV-1 integrase resistance among antiretroviral treatment naive and experienced patients from Northwestern Poland
por: Parczewski, Miłosz, et al.
Publicado: (2012)

HIV-2 Integrase Variation in Integrase Inhibitor-Naïve Adults in Senegal, West Africa
por: Gottlieb, Geoffrey S., et al.
Publicado: (2011)

Increasing trend of transmitted integrase inhibitor resistance in a cohort of antiretroviral therapy-naive people living with HIV
por: Muccini, Camilla, et al.
Publicado: (2023)

Integrase Strand Transfer Inhibitor Resistance Mutations in Antiretroviral Treatment-naïve Patients in Korea: a Prospective, Observational Study
por: Kim, Yeonjae, et al.
Publicado: (2018)

Absence of Integrase Inhibitor-Associated Resistance Among Antiretroviral Therapy-Naïve HIV-1-Infected Adults in Guangdong Province, China, in 2018
por: Lan, Yun, et al.
Publicado: (2020)

Weight and Metabolic Outcomes in Naïve HIV Patients Treated with Integrase Inhibitor-Based Antiretroviral Therapy: A Systematic Review and Meta-Analysis
por: Valenzuela-Rodriguez, German, et al.
Publicado: (2023)

Integrase Inhibitor Resistance Mechanisms and Structural Characteristics in Antiretroviral Therapy-Experienced, Integrase Inhibitor-Naive Adults with HIV-1 Infection Treated with Dolutegravir plus Two Nucleoside Reverse Transcriptase Inhibitors in the DAWNING Study
por: Underwood, Mark, et al.
Publicado: (2022)

Resistance to new antiretrovirals (ETV, anti-integrases, entry inhibitors)
por: Ceccherini-Silberstein, Francesca
Publicado: (2010)

Biochemical Characterization of Novel Retroviral Integrase Proteins
por: Ballandras-Colas, Allison, et al.
Publicado: (2013)

Emergent dolutegravir resistance in integrase-naïve, treatment experienced patients from Zimbabwe
por: Mandikiyana Chirimuta, Linda A., et al.
Publicado: (2022)

HIV-1 integrase polymorphisms are associated with prior antiretroviral drug exposure
por: van Hal, Sebastiaan J, et al.
Publicado: (2009)

Effects of Combined CCR5/Integrase Inhibitors-Based Regimen on Mucosal Immunity in HIV-Infected Patients Naïve to Antiretroviral Therapy: A Pilot Randomized Trial
por: Serrano-Villar, Sergio, et al.
Publicado: (2016)

Primary resistance against integrase strand transfer inhibitors in integrase strand transfer inhibitor-naive patients failing first- and second-line ART in Tanzania
por: Henerico, Shimba, et al.
Publicado: (2022)

Choice of the initial antiretroviral treatment for HIV-positive individuals in the era of integrase inhibitors
por: Alejos, Belén, et al.
Publicado: (2019)

Correction: Effects of Combined CCR5/Integrase Inhibitors-Based Regimen on Mucosal Immunity in HIV-Infected Patients Naïve to Antiretroviral Therapy: A Pilot Randomized Trial
por: Serrano-Villar, Sergio, et al.
Publicado: (2016)

Correction: Effects of Combined CCR5/Integrase Inhibitors-Based Regimen on Mucosal Immunity in HIV-Infected Patients Naïve to Antiretroviral Therapy: A Pilot Randomized Trial
por: Serrano-Villar, Sergio, et al.
Publicado: (2017)

A Comprehensive Review of Liver Allograft Fibrosis and Steatosis: From Cause to Diagnosis
por: Rabindranath, Madhumitha, et al.
Publicado: (2023)

Prevention of mother-to-child transmission: experience of a Portuguese centre
por: Piñeiro, Carmela, et al.
Publicado: (2014)

Raltegravir, elvitegravir, and metoogravir: the birth of "me-too" HIV-1 integrase inhibitors
por: Serrao, Erik, et al.
Publicado: (2009)

Raltegravir, elvitegravir, and metoogravir: the birth of "me-too" HIV-1 integrase inhibitors
por: Serrao, Erik, et al.
Publicado: (2009)

Assessment of Noninvasive Markers of Steatosis and Liver Fibrosis in Human Immunodeficiency Virus-Monoinfected Patients on Stable Antiretroviral Regimens
por: Busca, C, et al.
Publicado: (2022)

952. Weight-Gain in Treatment Naive Newly Diagnosed HIV-Infected Persons After Initiation on Integrase Strand Inhibitor Based Treatment Regimens
por: Szep, Zsofia, et al.
Publicado: (2020)

Predictive factors associated with liver fibrosis and steatosis by transient elastography in patients with HIV mono‐infection under long‐term combined antiretroviral therapy
por: Perazzo, Hugo, et al.
Publicado: (2018)

Drug Resistance to HIV-1 Integrase Inhibitors Among Treatment-Naive Patients in Beijing, China
por: Yu, Fengting, et al.
Publicado: (2022)

HIV/HCV-coinfection: which role can new antiretrovirals such as integrase inhibitors play?
por: Vogel, Martin, et al.
Publicado: (2009)

Hepatic steatosis in patients with HIV-Hepatitis C Virus coinfection: is it associated with antiretroviral therapy and more advanced hepatic fibrosis?
por: Verma, Sumita, et al.
Publicado: (2008)

Transmitted antiretroviral drug resistance in treatment naïve HIV-infected persons in London in 2011 to 2013
por: McFaul, Katie, et al.
Publicado: (2014)

Hepatic Fibrosis and Steatosis in Metabolic Syndrome
por: Gangireddy, Venu Gopala Reddy, et al.
Publicado: (2022)

Genetic Analysis of HIV-1 Integrase Sequences from Treatment Naive Individuals in Northeastern South Africa
por: Bessong, Pascal Obong, et al.
Publicado: (2013)

Occurrence of the S230R integrase strand inhibitor mutation in a treatment-naïve individual case report
por: Gudipati, Smitha, et al.
Publicado: (2020)

Effects of Integrase Inhibitor–Based ART on the NLRP3 Inflammasome Among ART-Naïve People With HIV
por: Toribio, Mabel, et al.
Publicado: (2020)

Low Frequency of Integrase Inhibitor Resistance Mutations Among Therapy-Naïve HIV Patients in Southeast China
por: Lai, Jinglan, et al.
Publicado: (2021)

Transmitted Drug Resistance Against Integrase Strand Transfer Inhibitors in Iranian HIV-Infected Naïve Patients
por: Hashempour, Ava, et al.
Publicado: (2023)

Virological and Immunological Outcomes of an Intensified Four-Drug versus a Standard Three-Drug Antiretroviral Regimen, Both Integrase Strand Transfer Inhibitor-Based, in Primary HIV Infection
por: Mondi, Annalisa, et al.
Publicado: (2022)

Initiating the antiretroviral therapy in treatment-naïve patients
por: Benea, Elisabeta, et al.
Publicado: (2014)

A targeted DNA substrate mechanism for the inhibition of HIV‐1 integrase by inhibitors with antiretroviral activity
por: Ammar, Farah F., et al.
Publicado: (2016)

Altered adipose tissue macrophage populations in people with HIV on integrase inhibitor-containing antiretroviral therapy
por: Vakili, Sarah, et al.
Publicado: (2022)

Integrase and integration: biochemical activities of HIV-1 integrase
por: Delelis, Olivier, et al.
Publicado: (2008)

Cardiac Effects of Antiretroviral-Naïve versus Antiretroviral-Exposed HIV Infection in Children
por: Idris, Nikmah S., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_38l156b050dnn1g6oug8e3ibef