MKRN1 promotes colorectal cancer metastasis by activating the TGF-β signalling pathway through SNIP1 protein degradation

BACKGROUND: The Makorin ring finger protein 1 (MKRN1) gene, also called RNF61, is located on the long arm of chromosome 7 and is a member of the RING finger protein family. The E3 ubiquitin ligase MKRN1 is closely linked to tumour development, but the exact mechanism needs to be elucidated. In this...

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Detalles Bibliográficos
Autores principales: Zhang, Yi, Li, Qin-shan, Liu, Hong-lin, Tang, Hong-ting, Yang, Han-lin, Wu, Dao-qiu, Huang, Yu-ying, Li, Li-cheng, Liu, Li-hong, Li, Meng-xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10464235/
https://www.ncbi.nlm.nih.gov/pubmed/37620897
http://dx.doi.org/10.1186/s13046-023-02788-w

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