The circadian clock circuitry modulates leukemia initiating cell activity in T-cell acute lymphoblastic leukemia

BACKGROUND: T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological malignancy, characterized by restricted cellular subsets with asymmetrically enriched leukemia initiating cell (LIC) activity. Nonetheless, it is still unclear which signaling programs promote LIC maintenance and...

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Detalles Bibliográficos
Autores principales: Murgo, Emanuele, De Santis, Elisabetta, Sansico, Francesca, Melocchi, Valentina, Colangelo, Tommaso, Padovano, Costanzo, Colucci, Mattia, Carbone, Annalucia, Totti, Beatrice, Basti, Alireza, Gottschlich, Lisa, Relogio, Angela, Capitanio, Nazzareno, Bianchi, Fabrizio, Mazzoccoli, Gianluigi, Giambra, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10464343/
https://www.ncbi.nlm.nih.gov/pubmed/37620852
http://dx.doi.org/10.1186/s13046-023-02799-7

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