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Correlation of toxicities and efficacies of pemetrexed with clinical factors and single-nucleotide polymorphisms: a prospective observational study

BACKGROUND: Pemetrexed is an efficacious multi-targeted antifolate with acceptable toxicity for non-squamous non-small cell lung cancer (non-Sq NSCLC) and malignant pleural mesothelioma. Vitamin B12 and folic acid as premedication can reduce the frequency of severe toxicities of pemetrexed chemother...

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Detalles Bibliográficos
Autores principales:	Takeda, Yuichiro, Naka, Go, Katsuya, Yuki, Kobayashi, Konomi, Suzuki, Manabu, Hashimoto, Masao, Hirano, Satoshi, Uemura, Yukari
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10464354/ https://www.ncbi.nlm.nih.gov/pubmed/37633908 http://dx.doi.org/10.1186/s12885-023-11257-8

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