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Characterization of novel bacteriophage PSKP16 and its therapeutic potential against β-lactamase and biofilm producer strain of K2-Hypervirulent Klebsiella pneumoniae pneumonia infection in mice model

BACKGROUND: Severe infections caused by β- lactamase producers, hypervirulent Klebsiella pneumoniae (BhvKp) with K2 serotype, highlight emergency need for new therapeutic strategies against this pathogen. We aimed to assess the efficacy of a novel phage, PSKP16, in the treating of pneumonia induced...

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Detalles Bibliográficos
Autores principales: Rahimi, Sara, Bakht, Mehdi, Javadi, Amir, Foroughi, Farshad, Marashi, Seyed Mahmoud Amin, Nikkhahi, Farhad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10464470/
https://www.ncbi.nlm.nih.gov/pubmed/37612659
http://dx.doi.org/10.1186/s12866-023-02979-7