Novel flurbiprofen clubbed oxadiazole derivatives as potential urease inhibitors and their molecular docking study

In this study, twenty eight novel oxadiazole derivatives (5–32) of the marketed available non-steroidal anti-inflammatory drug (NSAID), (S)-flurbiprofen (1), were synthesized via I(2) mediated cyclo-addition reaction in better yields. The synthesized hydrazone-Schiff bases were cyclized with iodine...

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Detalles Bibliográficos
Autores principales: Ahmad, Sajjad, Khan, Momin, Alam, Aftab, Ajmal, Amar, Wadood, Abdul, Khan, Azim, AlAsmari, Abdullah F., Alharbi, Metab, Alshammari, Abdulrahman, Shakoor, Abdul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10464598/
https://www.ncbi.nlm.nih.gov/pubmed/37649663
http://dx.doi.org/10.1039/d3ra03841f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10464598/
https://www.ncbi.nlm.nih.gov/pubmed/37649663
http://dx.doi.org/10.1039/d3ra03841f

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