In Utero Electroporated Neurons for Medium-Throughput Screening of Compounds Regulating Neuron Morphology

Several neurodevelopmental disorders are associated with increased mTOR activity that results in pathogenic neuronal dysmorphogenesis (i.e., soma and dendrite overgrowth), leading to circuit alterations associated with epilepsy and neurologic disabilities. Although an mTOR analog is approved for the...

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Detalles Bibliográficos
Autores principales: Sokolov, Aidan M., Aurich, Mariana, Bordey, Angélique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2023
Materias:
Research Article: Methods/New Tools
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10464655/
https://www.ncbi.nlm.nih.gov/pubmed/37620147
http://dx.doi.org/10.1523/ENEURO.0160-23.2023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10464655/
https://www.ncbi.nlm.nih.gov/pubmed/37620147
http://dx.doi.org/10.1523/ENEURO.0160-23.2023

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