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In Utero Electroporated Neurons for Medium-Throughput Screening of Compounds Regulating Neuron Morphology
Several neurodevelopmental disorders are associated with increased mTOR activity that results in pathogenic neuronal dysmorphogenesis (i.e., soma and dendrite overgrowth), leading to circuit alterations associated with epilepsy and neurologic disabilities. Although an mTOR analog is approved for the...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Society for Neuroscience
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10464655/ https://www.ncbi.nlm.nih.gov/pubmed/37620147 http://dx.doi.org/10.1523/ENEURO.0160-23.2023 |