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Safety and efficacy of Sorbiflore(®) ADVANCE (Lactobacillus rhamnosus CNCM I‐3698 and Lactobacillus farciminis CNCM I‐3699) as a feed additive for chickens for fattening

Following a request from the European Commission, the EFSA Panel on Additives and products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of Sorbiflore(®) ADVANCE when used as a zootechnical feed additive for chickens for fattening. So...

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Autores principales: Bampidis, Vasileios, Azimonti, Giovanna, Bastos, Maria de Lourdes, Christensen, Henrik, Dusemund, Birgit, Kos Durjava, Mojca, Kouba, Maryline, López‐Alonso, Marta, López Puente, Secundino, Marcon, Francesca, Mayo, Baltasar, Pechová, Alena, Petkova, Mariana, Ramos, Fernando, Sanz, Yolanda, Villa, Roberto Edoardo, Woutersen, Ruud, Cocconcelli, Pier Sandro, Glandorf, Boet, Prieto Maradona, Miguel, Saarela, Maria, Rychen, Guido, Pettenati, Elisa, Brozzi, Rosella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10464668/
https://www.ncbi.nlm.nih.gov/pubmed/37649498
http://dx.doi.org/10.2903/j.efsa.2020.6080
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author Bampidis, Vasileios
Azimonti, Giovanna
Bastos, Maria de Lourdes
Christensen, Henrik
Dusemund, Birgit
Kos Durjava, Mojca
Kouba, Maryline
López‐Alonso, Marta
López Puente, Secundino
Marcon, Francesca
Mayo, Baltasar
Pechová, Alena
Petkova, Mariana
Ramos, Fernando
Sanz, Yolanda
Villa, Roberto Edoardo
Woutersen, Ruud
Cocconcelli, Pier Sandro
Glandorf, Boet
Prieto Maradona, Miguel
Saarela, Maria
Rychen, Guido
Pettenati, Elisa
Brozzi, Rosella
author_facet Bampidis, Vasileios
Azimonti, Giovanna
Bastos, Maria de Lourdes
Christensen, Henrik
Dusemund, Birgit
Kos Durjava, Mojca
Kouba, Maryline
López‐Alonso, Marta
López Puente, Secundino
Marcon, Francesca
Mayo, Baltasar
Pechová, Alena
Petkova, Mariana
Ramos, Fernando
Sanz, Yolanda
Villa, Roberto Edoardo
Woutersen, Ruud
Cocconcelli, Pier Sandro
Glandorf, Boet
Prieto Maradona, Miguel
Saarela, Maria
Rychen, Guido
Pettenati, Elisa
Brozzi, Rosella
collection PubMed
description Following a request from the European Commission, the EFSA Panel on Additives and products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of Sorbiflore(®) ADVANCE when used as a zootechnical feed additive for chickens for fattening. Sorbiflore(®) ADVANCE is an additive resulting from the fermentation of milk‐based broth with Lactobacillus rhamnosus CNCM I‐3698 and Lactobacillus farciminis CNCM I‐3699. Sorbiflore(®) ADVANCE is intended for use in feed for chickens for fattening at the minimum concentration of 5 × 10(7) Viable Forming Units (VFU)/kg and the maximum concentration of 2 × 10(8) VFU/kg complete feed. The data submitted did not allow a full characterisation of the additive, and therefore, uncertainty remains on the nature of the product in terms of viability, on the ratio between the active agents and on the stability and homogeneity of the additive. The active agents fulfil the requirements of the Qualified Presumption of Safety (QPS) approach to the assessment of safety and no concerns are expected from other components of the additive. Consequently, Sorbiflore(®) ADVANCE is presumed to be safe for the target animals, consumers of products from animals receiving the additive and the environment. The additive should be considered a respiratory sensitiser. In the absence of data, no conclusions can be drawn on the irritancy of Sorbiflore(®) ADVANCE to skin and eyes and on its dermal sensitisation potential. Sorbiflore(®) ADVANCE at 2 × 10(8) VFU/kg feed has the potential to be efficacious in chickens for fattening.
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spelling pubmed-104646682023-08-30 Safety and efficacy of Sorbiflore(®) ADVANCE (Lactobacillus rhamnosus CNCM I‐3698 and Lactobacillus farciminis CNCM I‐3699) as a feed additive for chickens for fattening Bampidis, Vasileios Azimonti, Giovanna Bastos, Maria de Lourdes Christensen, Henrik Dusemund, Birgit Kos Durjava, Mojca Kouba, Maryline López‐Alonso, Marta López Puente, Secundino Marcon, Francesca Mayo, Baltasar Pechová, Alena Petkova, Mariana Ramos, Fernando Sanz, Yolanda Villa, Roberto Edoardo Woutersen, Ruud Cocconcelli, Pier Sandro Glandorf, Boet Prieto Maradona, Miguel Saarela, Maria Rychen, Guido Pettenati, Elisa Brozzi, Rosella EFSA J Scientific Opinion Following a request from the European Commission, the EFSA Panel on Additives and products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of Sorbiflore(®) ADVANCE when used as a zootechnical feed additive for chickens for fattening. Sorbiflore(®) ADVANCE is an additive resulting from the fermentation of milk‐based broth with Lactobacillus rhamnosus CNCM I‐3698 and Lactobacillus farciminis CNCM I‐3699. Sorbiflore(®) ADVANCE is intended for use in feed for chickens for fattening at the minimum concentration of 5 × 10(7) Viable Forming Units (VFU)/kg and the maximum concentration of 2 × 10(8) VFU/kg complete feed. The data submitted did not allow a full characterisation of the additive, and therefore, uncertainty remains on the nature of the product in terms of viability, on the ratio between the active agents and on the stability and homogeneity of the additive. The active agents fulfil the requirements of the Qualified Presumption of Safety (QPS) approach to the assessment of safety and no concerns are expected from other components of the additive. Consequently, Sorbiflore(®) ADVANCE is presumed to be safe for the target animals, consumers of products from animals receiving the additive and the environment. The additive should be considered a respiratory sensitiser. In the absence of data, no conclusions can be drawn on the irritancy of Sorbiflore(®) ADVANCE to skin and eyes and on its dermal sensitisation potential. Sorbiflore(®) ADVANCE at 2 × 10(8) VFU/kg feed has the potential to be efficacious in chickens for fattening. John Wiley and Sons Inc. 2020-05-04 /pmc/articles/PMC10464668/ /pubmed/37649498 http://dx.doi.org/10.2903/j.efsa.2020.6080 Text en © 2020 European Food Safety Authority. EFSA Journal published by John Wiley and Sons Ltd on behalf of European Food Safety Authority. https://creativecommons.org/licenses/by-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nd/4.0/ (https://creativecommons.org/licenses/by-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited and no modifications or adaptations are made.
spellingShingle Scientific Opinion
Bampidis, Vasileios
Azimonti, Giovanna
Bastos, Maria de Lourdes
Christensen, Henrik
Dusemund, Birgit
Kos Durjava, Mojca
Kouba, Maryline
López‐Alonso, Marta
López Puente, Secundino
Marcon, Francesca
Mayo, Baltasar
Pechová, Alena
Petkova, Mariana
Ramos, Fernando
Sanz, Yolanda
Villa, Roberto Edoardo
Woutersen, Ruud
Cocconcelli, Pier Sandro
Glandorf, Boet
Prieto Maradona, Miguel
Saarela, Maria
Rychen, Guido
Pettenati, Elisa
Brozzi, Rosella
Safety and efficacy of Sorbiflore(®) ADVANCE (Lactobacillus rhamnosus CNCM I‐3698 and Lactobacillus farciminis CNCM I‐3699) as a feed additive for chickens for fattening
title Safety and efficacy of Sorbiflore(®) ADVANCE (Lactobacillus rhamnosus CNCM I‐3698 and Lactobacillus farciminis CNCM I‐3699) as a feed additive for chickens for fattening
title_full Safety and efficacy of Sorbiflore(®) ADVANCE (Lactobacillus rhamnosus CNCM I‐3698 and Lactobacillus farciminis CNCM I‐3699) as a feed additive for chickens for fattening
title_fullStr Safety and efficacy of Sorbiflore(®) ADVANCE (Lactobacillus rhamnosus CNCM I‐3698 and Lactobacillus farciminis CNCM I‐3699) as a feed additive for chickens for fattening
title_full_unstemmed Safety and efficacy of Sorbiflore(®) ADVANCE (Lactobacillus rhamnosus CNCM I‐3698 and Lactobacillus farciminis CNCM I‐3699) as a feed additive for chickens for fattening
title_short Safety and efficacy of Sorbiflore(®) ADVANCE (Lactobacillus rhamnosus CNCM I‐3698 and Lactobacillus farciminis CNCM I‐3699) as a feed additive for chickens for fattening
title_sort safety and efficacy of sorbiflore(®) advance (lactobacillus rhamnosus cncm i‐3698 and lactobacillus farciminis cncm i‐3699) as a feed additive for chickens for fattening
topic Scientific Opinion
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10464668/
https://www.ncbi.nlm.nih.gov/pubmed/37649498
http://dx.doi.org/10.2903/j.efsa.2020.6080
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