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Safety and efficacy of IMP (disodium 5′‐inosinate) produced by fermentation with Corynebacterium stationis KCCM 80161 for all animal species
Following a request from the European Commission, the Panel on Additives and Products or substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of disodium 5′‐inosinate (IMP) produced by fermentation using Corynebacterium stationis KCCM 80161 whe...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10464688/ https://www.ncbi.nlm.nih.gov/pubmed/37649505 http://dx.doi.org/10.2903/j.efsa.2020.6140 |
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author | Bampidis, Vasileios Azimonti, Giovanna Bastos, Maria de Lourdes Christensen, Henrik Dusemund, Birgit Kouba, Maryline Kos Durjava, Mojca López‐Alonso, Marta López Puente, Secundino Marcon, Francesca Mayo, Baltasar Pechová, Alena Petkova, Mariana Ramos, Fernando Sanz, Yolanda Villa, Roberto Edoardo Woutersen, Ruud Cocconcelli, Pier Sandro Glandorf, Boet Herman, Lieve Prieto Maradona, Miguel Saarela, Maria Tosti, Luca Anguita, Montserrat Galobart, Jaume Holczknecht, Orsolya Manini, Paola Pizzo, Fabiola Tarrés‐Call, Jordi Pettenati, Elisa |
author_facet | Bampidis, Vasileios Azimonti, Giovanna Bastos, Maria de Lourdes Christensen, Henrik Dusemund, Birgit Kouba, Maryline Kos Durjava, Mojca López‐Alonso, Marta López Puente, Secundino Marcon, Francesca Mayo, Baltasar Pechová, Alena Petkova, Mariana Ramos, Fernando Sanz, Yolanda Villa, Roberto Edoardo Woutersen, Ruud Cocconcelli, Pier Sandro Glandorf, Boet Herman, Lieve Prieto Maradona, Miguel Saarela, Maria Tosti, Luca Anguita, Montserrat Galobart, Jaume Holczknecht, Orsolya Manini, Paola Pizzo, Fabiola Tarrés‐Call, Jordi Pettenati, Elisa |
collection | PubMed |
description | Following a request from the European Commission, the Panel on Additives and Products or substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of disodium 5′‐inosinate (IMP) produced by fermentation using Corynebacterium stationis KCCM 80161 when used as a sensory additive (flavouring compound) in feed and water for drinking for all animal species. The production strain is not genetically modified. Viable cells of the production strain were not detected in the final additive. The additive does not give rise to any safety concern regarding the production strain. IMP produced using C. stationis KCCM 80161 is considered safe for the target species, for the consumer and for the environment. IMP produced using C. stationis KCCM 80161 is considered not toxic by inhalation, not irritant to skin or eyes and not a dermal sensitiser. The FEEDAP Panel expressed reservations on the use of the additive in water for drinking due to concerns on its impact on the hygienic conditions of the water. The Panel concluded that the additive is efficacious to contribute to the flavour of feed. |
format | Online Article Text |
id | pubmed-10464688 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-104646882023-08-30 Safety and efficacy of IMP (disodium 5′‐inosinate) produced by fermentation with Corynebacterium stationis KCCM 80161 for all animal species Bampidis, Vasileios Azimonti, Giovanna Bastos, Maria de Lourdes Christensen, Henrik Dusemund, Birgit Kouba, Maryline Kos Durjava, Mojca López‐Alonso, Marta López Puente, Secundino Marcon, Francesca Mayo, Baltasar Pechová, Alena Petkova, Mariana Ramos, Fernando Sanz, Yolanda Villa, Roberto Edoardo Woutersen, Ruud Cocconcelli, Pier Sandro Glandorf, Boet Herman, Lieve Prieto Maradona, Miguel Saarela, Maria Tosti, Luca Anguita, Montserrat Galobart, Jaume Holczknecht, Orsolya Manini, Paola Pizzo, Fabiola Tarrés‐Call, Jordi Pettenati, Elisa EFSA J Scientific Opinion Following a request from the European Commission, the Panel on Additives and Products or substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of disodium 5′‐inosinate (IMP) produced by fermentation using Corynebacterium stationis KCCM 80161 when used as a sensory additive (flavouring compound) in feed and water for drinking for all animal species. The production strain is not genetically modified. Viable cells of the production strain were not detected in the final additive. The additive does not give rise to any safety concern regarding the production strain. IMP produced using C. stationis KCCM 80161 is considered safe for the target species, for the consumer and for the environment. IMP produced using C. stationis KCCM 80161 is considered not toxic by inhalation, not irritant to skin or eyes and not a dermal sensitiser. The FEEDAP Panel expressed reservations on the use of the additive in water for drinking due to concerns on its impact on the hygienic conditions of the water. The Panel concluded that the additive is efficacious to contribute to the flavour of feed. John Wiley and Sons Inc. 2020-05-27 /pmc/articles/PMC10464688/ /pubmed/37649505 http://dx.doi.org/10.2903/j.efsa.2020.6140 Text en © 2020 European Food Safety Authority. EFSA Journal published by John Wiley and Sons Ltd on behalf of European Food Safety Authority. https://creativecommons.org/licenses/by-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nd/4.0/ (https://creativecommons.org/licenses/by-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited and no modifications or adaptations are made. |
spellingShingle | Scientific Opinion Bampidis, Vasileios Azimonti, Giovanna Bastos, Maria de Lourdes Christensen, Henrik Dusemund, Birgit Kouba, Maryline Kos Durjava, Mojca López‐Alonso, Marta López Puente, Secundino Marcon, Francesca Mayo, Baltasar Pechová, Alena Petkova, Mariana Ramos, Fernando Sanz, Yolanda Villa, Roberto Edoardo Woutersen, Ruud Cocconcelli, Pier Sandro Glandorf, Boet Herman, Lieve Prieto Maradona, Miguel Saarela, Maria Tosti, Luca Anguita, Montserrat Galobart, Jaume Holczknecht, Orsolya Manini, Paola Pizzo, Fabiola Tarrés‐Call, Jordi Pettenati, Elisa Safety and efficacy of IMP (disodium 5′‐inosinate) produced by fermentation with Corynebacterium stationis KCCM 80161 for all animal species |
title | Safety and efficacy of IMP (disodium 5′‐inosinate) produced by fermentation with Corynebacterium stationis
KCCM 80161 for all animal species |
title_full | Safety and efficacy of IMP (disodium 5′‐inosinate) produced by fermentation with Corynebacterium stationis
KCCM 80161 for all animal species |
title_fullStr | Safety and efficacy of IMP (disodium 5′‐inosinate) produced by fermentation with Corynebacterium stationis
KCCM 80161 for all animal species |
title_full_unstemmed | Safety and efficacy of IMP (disodium 5′‐inosinate) produced by fermentation with Corynebacterium stationis
KCCM 80161 for all animal species |
title_short | Safety and efficacy of IMP (disodium 5′‐inosinate) produced by fermentation with Corynebacterium stationis
KCCM 80161 for all animal species |
title_sort | safety and efficacy of imp (disodium 5′‐inosinate) produced by fermentation with corynebacterium stationis
kccm 80161 for all animal species |
topic | Scientific Opinion |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10464688/ https://www.ncbi.nlm.nih.gov/pubmed/37649505 http://dx.doi.org/10.2903/j.efsa.2020.6140 |
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