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Large-scale template-based structural modeling of T-cell receptors with known antigen specificity reveals complementarity features
INTRODUCTION: T-cell receptor (TCR) recognition of foreign peptides presented by the major histocompatibility complex (MHC) initiates the adaptive immune response against pathogens. While a large number of TCR sequences specific to different antigenic peptides are known to date, the structural data...
Autores principales: | Shcherbinin, Dmitrii S., Karnaukhov, Vadim K., Zvyagin, Ivan V., Chudakov, Dmitriy M., Shugay, Mikhail |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10464843/ https://www.ncbi.nlm.nih.gov/pubmed/37649481 http://dx.doi.org/10.3389/fimmu.2023.1224969 |
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