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Large-scale template-based structural modeling of T-cell receptors with known antigen specificity reveals complementarity features

INTRODUCTION: T-cell receptor (TCR) recognition of foreign peptides presented by the major histocompatibility complex (MHC) initiates the adaptive immune response against pathogens. While a large number of TCR sequences specific to different antigenic peptides are known to date, the structural data...

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Detalles Bibliográficos
Autores principales: Shcherbinin, Dmitrii S., Karnaukhov, Vadim K., Zvyagin, Ivan V., Chudakov, Dmitriy M., Shugay, Mikhail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10464843/
https://www.ncbi.nlm.nih.gov/pubmed/37649481
http://dx.doi.org/10.3389/fimmu.2023.1224969

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