Cargando…
Phase 2 Results Indicate Evenamide, A Selective Modulator of Glutamate Release, Is Associated With Clinically Important Long-Term Efficacy When Added to an Antipsychotic in Patients With Treatment-Resistant Schizophrenia
Results from a pilot, 6-week, randomized, open-label, rater-blinded study, with 46-week extension, indicate very good tolerability with exceptional, clinically important, increasing efficacy of evenamide (7.5, 15, and 30 mg bid), a glutamate modulator, as add-on treatment to antipsychotics in 161 tr...
Autores principales: | Anand, Ravi, Turolla, Alessio, Chinellato, Giovanni, Roy, Arjun, Hartman, Richard D |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10464926/ https://www.ncbi.nlm.nih.gov/pubmed/37349110 http://dx.doi.org/10.1093/ijnp/pyad035 |
Ejemplares similares
-
Evenamide, as an add-on to antipsychotics, benefits patients with treatment resistant schizophrenia: 6-month interim results from the first 100 patients in an ongoing international randomized study
por: Anand, R., et al.
Publicado: (2023) -
T48. ANTIPSYCHOTIC EFFICACY OF EVENAMIDE (NW-3509) IS DUE TO MODULATION OF GLUTAMATERGIC DYSREGULATION
por: Anand, Ravi, et al.
Publicado: (2018) -
Characterization of “Responder” in patients with Treatment-Resistant Schizophrenia (TRS) treated with a new antipsychotic added to their current antipsychotic monotherapy
por: Anand, R., et al.
Publicado: (2023) -
T36. THE ANTIPSYCHOTIC-LIKE PROPERTIES OF EVENAMIDE (NW-3509) REFLECT THE MODULATION OF GLUTAMATERGIC DYSREGULATION
por: Bortolato, Marco, et al.
Publicado: (2018) -
Platelet glutamate dehydrogenase activity and efficacy of antipsychotic therapy in patients with schizophrenia
por: Savushkina, Olga K., et al.
Publicado: (2020)