Glycosylated extracellular mucin domains protect against SARS-CoV-2 infection at the respiratory surface

Mucins play an essential role in protecting the respiratory tract against microbial infections while also acting as binding sites for bacterial and viral adhesins. The heavily O-glycosylated gel-forming mucins MUC5AC and MUC5B eliminate pathogens by mucociliary clearance. Transmembrane mucins MUC1,...

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Detalles Bibliográficos
Autores principales: Chatterjee, Maitrayee, Huang, Liane Z. X., Mykytyn, Anna Z., Wang, Chunyan, Lamers, Mart M., Westendorp, Bart, Wubbolts, Richard W., van Putten, Jos P. M., Bosch, Berend-Jan, Haagmans, Bart L., Strijbis, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10464970/
https://www.ncbi.nlm.nih.gov/pubmed/37561789
http://dx.doi.org/10.1371/journal.ppat.1011571

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