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BALDR: A Web-based platform for informed comparison and prioritization of biomarker candidates for type 2 diabetes mellitus
Novel biomarkers are key to addressing the ongoing pandemic of type 2 diabetes mellitus. While new technologies have improved the potential of identifying such biomarkers, at the same time there is an increasing need for informed prioritization to ensure efficient downstream verification. We have bu...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10464978/ https://www.ncbi.nlm.nih.gov/pubmed/37590326 http://dx.doi.org/10.1371/journal.pcbi.1011403 |
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author | Lundgaard, Agnete T. Burdet, Frédéric Siggaard, Troels Westergaard, David Vagiaki, Danai Cantwell, Lisa Röder, Timo Vistisen, Dorte Sparsø, Thomas Giordano, Giuseppe N. Ibberson, Mark Banasik, Karina Brunak, Søren |
author_facet | Lundgaard, Agnete T. Burdet, Frédéric Siggaard, Troels Westergaard, David Vagiaki, Danai Cantwell, Lisa Röder, Timo Vistisen, Dorte Sparsø, Thomas Giordano, Giuseppe N. Ibberson, Mark Banasik, Karina Brunak, Søren |
author_sort | Lundgaard, Agnete T. |
collection | PubMed |
description | Novel biomarkers are key to addressing the ongoing pandemic of type 2 diabetes mellitus. While new technologies have improved the potential of identifying such biomarkers, at the same time there is an increasing need for informed prioritization to ensure efficient downstream verification. We have built BALDR, an automated pipeline for biomarker comparison and prioritization in the context of diabetes. BALDR includes protein, gene, and disease data from major public repositories, text-mining data, and human and mouse experimental data from the IMI2 RHAPSODY consortium. These data are provided as easy-to-read figures and tables enabling direct comparison of up to 20 biomarker candidates for diabetes through the public website https://baldr.cpr.ku.dk. |
format | Online Article Text |
id | pubmed-10464978 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-104649782023-08-30 BALDR: A Web-based platform for informed comparison and prioritization of biomarker candidates for type 2 diabetes mellitus Lundgaard, Agnete T. Burdet, Frédéric Siggaard, Troels Westergaard, David Vagiaki, Danai Cantwell, Lisa Röder, Timo Vistisen, Dorte Sparsø, Thomas Giordano, Giuseppe N. Ibberson, Mark Banasik, Karina Brunak, Søren PLoS Comput Biol Software Novel biomarkers are key to addressing the ongoing pandemic of type 2 diabetes mellitus. While new technologies have improved the potential of identifying such biomarkers, at the same time there is an increasing need for informed prioritization to ensure efficient downstream verification. We have built BALDR, an automated pipeline for biomarker comparison and prioritization in the context of diabetes. BALDR includes protein, gene, and disease data from major public repositories, text-mining data, and human and mouse experimental data from the IMI2 RHAPSODY consortium. These data are provided as easy-to-read figures and tables enabling direct comparison of up to 20 biomarker candidates for diabetes through the public website https://baldr.cpr.ku.dk. Public Library of Science 2023-08-17 /pmc/articles/PMC10464978/ /pubmed/37590326 http://dx.doi.org/10.1371/journal.pcbi.1011403 Text en © 2023 Lundgaard et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Software Lundgaard, Agnete T. Burdet, Frédéric Siggaard, Troels Westergaard, David Vagiaki, Danai Cantwell, Lisa Röder, Timo Vistisen, Dorte Sparsø, Thomas Giordano, Giuseppe N. Ibberson, Mark Banasik, Karina Brunak, Søren BALDR: A Web-based platform for informed comparison and prioritization of biomarker candidates for type 2 diabetes mellitus |
title | BALDR: A Web-based platform for informed comparison and prioritization of biomarker candidates for type 2 diabetes mellitus |
title_full | BALDR: A Web-based platform for informed comparison and prioritization of biomarker candidates for type 2 diabetes mellitus |
title_fullStr | BALDR: A Web-based platform for informed comparison and prioritization of biomarker candidates for type 2 diabetes mellitus |
title_full_unstemmed | BALDR: A Web-based platform for informed comparison and prioritization of biomarker candidates for type 2 diabetes mellitus |
title_short | BALDR: A Web-based platform for informed comparison and prioritization of biomarker candidates for type 2 diabetes mellitus |
title_sort | baldr: a web-based platform for informed comparison and prioritization of biomarker candidates for type 2 diabetes mellitus |
topic | Software |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10464978/ https://www.ncbi.nlm.nih.gov/pubmed/37590326 http://dx.doi.org/10.1371/journal.pcbi.1011403 |
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