NCoR1 controls Mycobacterium tuberculosis growth in myeloid cells by regulating the AMPK-mTOR-TFEB axis

Mycobacterium tuberculosis (Mtb) defends host-mediated killing by repressing the autophagolysosome machinery. For the first time, we report NCoR1 co-repressor as a crucial host factor, controlling Mtb growth in myeloid cells by regulating both autophagosome maturation and lysosome biogenesis. We fou...

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Detalles Bibliográficos
Autores principales: Biswas, Viplov Kumar, Sen, Kaushik, Ahad, Abdul, Ghosh, Arup, Verma, Surbhi, Pati, Rashmirekha, Prusty, Subhasish, Nayak, Sourya Prakash, Podder, Sreeparna, Kumar, Dhiraj, Gupta, Bhawna, Raghav, Sunil Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465006/
https://www.ncbi.nlm.nih.gov/pubmed/37590294
http://dx.doi.org/10.1371/journal.pbio.3002231

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