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TLR7 activation at epithelial barriers promotes emergency myelopoiesis and lung antiviral immunity

Monocytes are heterogeneous innate effector leukocytes generated in the bone marrow and released into circulation in a CCR2-dependent manner. During infection or inflammation, myelopoiesis is modulated to rapidly meet the demand for more effector cells. Danger signals from peripheral tissues can inf...

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Detalles Bibliográficos
Autores principales: Jackson, William D, Giacomassi, Chiara, Ward, Sophie, Owen, Amber, Luis, Tiago C, Spear, Sarah, Woollard, Kevin J, Johansson, Cecilia, Strid, Jessica, Botto, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465127/
https://www.ncbi.nlm.nih.gov/pubmed/37566453
http://dx.doi.org/10.7554/eLife.85647