Changes in plasma alpha‐1 acid glycoprotein following hemorrhagic trauma: Possible role in dose differences of ALM drug therapy in rat and pig resuscitation

INTRODUCTION: The binding of drugs to plasma proteins is an important consideration in drug development. We have reported that the dose of adenosine, lidocaine, and magnesium (ALM) fluid therapy for resuscitation from hemorrhagic shock is nearly 3‐times higher for pigs than rats. Since lidocaine str...

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Detalles Bibliográficos
Autores principales: Letson, Hayley L., Morris, Jodie L., Dobson, Geoffrey P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465298/
https://www.ncbi.nlm.nih.gov/pubmed/37643751
http://dx.doi.org/10.1002/prp2.1133

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465298/
https://www.ncbi.nlm.nih.gov/pubmed/37643751
http://dx.doi.org/10.1002/prp2.1133

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