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Development of a growth-coupled selection platform for directed evolution of heme biosynthetic enzymes in Corynebacterium glutamicum

Heme is an important tetrapyrrole compound, and has been widely applied in food and medicine industries. Although microbial production of heme has been developed with metabolic engineering strategies during the past 20 years, the production levels are relatively low due to the multistep enzymatic pr...

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Detalles Bibliográficos
Autores principales: Zhou, Yingyu, Chen, Jiuzhou, Pu, Wei, Cai, Ningyun, Che, Bin, Yang, Jinxing, Wang, Mengmeng, Zhong, Shasha, Zuo, Xingtao, Wang, Depei, Wang, Yu, Zheng, Ping, Sun, Jibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465345/
https://www.ncbi.nlm.nih.gov/pubmed/37654705
http://dx.doi.org/10.3389/fbioe.2023.1236118