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Electrostatic interactions guide substrate recognition of the prokaryotic ubiquitin-like protein ligase PafA

Pupylation, a post-translational modification found in Mycobacterium tuberculosis and other Actinobacteria, involves the covalent attachment of prokaryotic ubiquitin-like protein (Pup) to lysines on target proteins by the ligase PafA (proteasome accessory factor A). Pupylated proteins, like ubiquiti...

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Detalles Bibliográficos
Autores principales: Block, Matthias F., Delley, Cyrille L., Keller, Lena M. L., Stuehlinger, Timo T., Weber-Ban, Eilika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465538/
https://www.ncbi.nlm.nih.gov/pubmed/37644028
http://dx.doi.org/10.1038/s41467-023-40807-8

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