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Electrostatic interactions guide substrate recognition of the prokaryotic ubiquitin-like protein ligase PafA
Pupylation, a post-translational modification found in Mycobacterium tuberculosis and other Actinobacteria, involves the covalent attachment of prokaryotic ubiquitin-like protein (Pup) to lysines on target proteins by the ligase PafA (proteasome accessory factor A). Pupylated proteins, like ubiquiti...
Autores principales: | Block, Matthias F., Delley, Cyrille L., Keller, Lena M. L., Stuehlinger, Timo T., Weber-Ban, Eilika |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465538/ https://www.ncbi.nlm.nih.gov/pubmed/37644028 http://dx.doi.org/10.1038/s41467-023-40807-8 |
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