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Evidence of natural selection in the mitochondrial-derived peptides humanin and SHLP6

Mitochondrial-derived peptides are encoded by mitochondrial DNA but have biological activity outside mitochondria. Eight of these are encoded by sequences within the mitochondrial 12S and 16S ribosomal genes: humanin, MOTS-c, and the six SHLP peptides, SHLP1-SHLP6. These peptides have various effect...

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Detalles Bibliográficos
Autores principales: Gruschus, James M., Morris, Daniel L., Tjandra, Nico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465549/
https://www.ncbi.nlm.nih.gov/pubmed/37644144
http://dx.doi.org/10.1038/s41598-023-41053-0