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Deep and fast label-free Dynamic Organellar Mapping

The Dynamic Organellar Maps (DOMs) approach combines cell fractionation and shotgun-proteomics for global profiling analysis of protein subcellular localization. Here, we enhance the performance of DOMs through data-independent acquisition (DIA) mass spectrometry. DIA-DOMs achieve twice the depth of...

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Detalles Bibliográficos
Autores principales: Schessner, Julia P., Albrecht, Vincent, Davies, Alexandra K., Sinitcyn, Pavel, Borner, Georg H. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465578/
https://www.ncbi.nlm.nih.gov/pubmed/37644046
http://dx.doi.org/10.1038/s41467-023-41000-7