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Deep and fast label-free Dynamic Organellar Mapping
The Dynamic Organellar Maps (DOMs) approach combines cell fractionation and shotgun-proteomics for global profiling analysis of protein subcellular localization. Here, we enhance the performance of DOMs through data-independent acquisition (DIA) mass spectrometry. DIA-DOMs achieve twice the depth of...
Autores principales: | Schessner, Julia P., Albrecht, Vincent, Davies, Alexandra K., Sinitcyn, Pavel, Borner, Georg H. H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465578/ https://www.ncbi.nlm.nih.gov/pubmed/37644046 http://dx.doi.org/10.1038/s41467-023-41000-7 |
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