Epigenetic regulation in major depression and other stress-related disorders: molecular mechanisms, clinical relevance and therapeutic potential

Major depressive disorder (MDD) is a chronic, generally episodic and debilitating disease that affects an estimated 300 million people worldwide, but its pathogenesis is poorly understood. The heritability estimate of MDD is 30–40%, suggesting that genetics alone do not account for most of the risk...

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Detalles Bibliográficos
Autores principales: Yuan, Minlan, Yang, Biao, Rothschild, Gerson, Mann, J. John, Sanford, Larry D., Tang, Xiangdong, Huang, Canhua, Wang, Chuang, Zhang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465587/
https://www.ncbi.nlm.nih.gov/pubmed/37644009
http://dx.doi.org/10.1038/s41392-023-01519-z

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