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Development of innovative methodology for determination of 6-thioguanine in whole blood erythrocytes by HPLC–PDA-based technique for medical diagnostics purposes

6-Thioguanine is an immunosuppressive drug, an analogue of guanine, applied to treat acute leukemia and inflammatory bowel disease. Excessive use of 6-thioguanine during clinical treatment may cause side effects. Moreover, providing a dose too low will be ineffective. Therefore, there is a critical...

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Detalles Bibliográficos
Autores principales:	Noga, Maciej, Zakrzewski, Marcin, Wianowska, Dorota, Gnatowski, Maciej, Paprotny, Łukasz, Jurowski, Kamil
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465597/ https://www.ncbi.nlm.nih.gov/pubmed/37644112 http://dx.doi.org/10.1038/s41598-023-41426-5

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