CSPG4 as a target for the specific killing of triple-negative breast cancer cells by a recombinant SNAP-tag-based antibody-auristatin F drug conjugate

PURPOSE: Triple-negative breast cancer (TNBC) is phenotypic of breast tumors lacking expression of the estrogen receptor (ER), the progesterone receptor (PgR), and the human epidermal growth factor receptor 2 (HER2). The paucity of well-defined molecular targets in TNBC, coupled with the increasing...

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Detalles Bibliográficos
Autores principales: Mungra, Neelakshi, Biteghe, Fleury A. N., Malindi, Zaria, Huysamen, Allan M., Karaan, Maryam, Hardcastle, Natasha S., Bunjun, Rubina, Chetty, Shivan, Naran, Krupa, Lang, Dirk, Richter, Wolfgang, Hunter, Roger, Barth, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465649/
https://www.ncbi.nlm.nih.gov/pubmed/37432459
http://dx.doi.org/10.1007/s00432-023-05031-3

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