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Antibacterial effect of Rubus chingii flower extract against multidrug-resistant bacteria

Rubus chingii is a well reputed member of Chinese traditional medicine system and is used for managing different ailments since historic times. The present report elucidates the growth impeding effect of R. chingii flower extract against multidrug resistant Escherichia coli, Klebsiella pneumoniae an...

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Autor principal: Saeed, Amir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465780/
https://www.ncbi.nlm.nih.gov/pubmed/37654834
http://dx.doi.org/10.6026/97320630018938
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author Saeed, Amir
author_facet Saeed, Amir
author_sort Saeed, Amir
collection PubMed
description Rubus chingii is a well reputed member of Chinese traditional medicine system and is used for managing different ailments since historic times. The present report elucidates the growth impeding effect of R. chingii flower extract against multidrug resistant Escherichia coli, Klebsiella pneumoniae and Staphylococcus aureus. The extracts were prepared using standard Soxhlet extraction method using ethanol, methanol and acetone as a solvent. The extracts were further subjected to agar streak method and the stains that showed their sensitivity were further evaluated for minimum inhibitor concentration (MIC) assessment through TCC method. Subsequently the MIC was further used for well diffusion assay. All the strains used in the study showed their sensitivity towards R. chingii flowers extract in respective solvents. Highest antibacterial activity was seen against E. coli. and S. aureus whereas the lowest activity was recorded against K. pneumoniae. Thus the study reported herewith provided an insight into the antibacterial efficacy of R. chingii flower extract against MDR E. coli., S. aureus and K. pneumoniae.
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spelling pubmed-104657802023-08-31 Antibacterial effect of Rubus chingii flower extract against multidrug-resistant bacteria Saeed, Amir Bioinformation Research Article Rubus chingii is a well reputed member of Chinese traditional medicine system and is used for managing different ailments since historic times. The present report elucidates the growth impeding effect of R. chingii flower extract against multidrug resistant Escherichia coli, Klebsiella pneumoniae and Staphylococcus aureus. The extracts were prepared using standard Soxhlet extraction method using ethanol, methanol and acetone as a solvent. The extracts were further subjected to agar streak method and the stains that showed their sensitivity were further evaluated for minimum inhibitor concentration (MIC) assessment through TCC method. Subsequently the MIC was further used for well diffusion assay. All the strains used in the study showed their sensitivity towards R. chingii flowers extract in respective solvents. Highest antibacterial activity was seen against E. coli. and S. aureus whereas the lowest activity was recorded against K. pneumoniae. Thus the study reported herewith provided an insight into the antibacterial efficacy of R. chingii flower extract against MDR E. coli., S. aureus and K. pneumoniae. Biomedical Informatics 2022-10-31 /pmc/articles/PMC10465780/ /pubmed/37654834 http://dx.doi.org/10.6026/97320630018938 Text en © 2022 Biomedical Informatics https://creativecommons.org/licenses/by/3.0/This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
spellingShingle Research Article
Saeed, Amir
Antibacterial effect of Rubus chingii flower extract against multidrug-resistant bacteria
title Antibacterial effect of Rubus chingii flower extract against multidrug-resistant bacteria
title_full Antibacterial effect of Rubus chingii flower extract against multidrug-resistant bacteria
title_fullStr Antibacterial effect of Rubus chingii flower extract against multidrug-resistant bacteria
title_full_unstemmed Antibacterial effect of Rubus chingii flower extract against multidrug-resistant bacteria
title_short Antibacterial effect of Rubus chingii flower extract against multidrug-resistant bacteria
title_sort antibacterial effect of rubus chingii flower extract against multidrug-resistant bacteria
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465780/
https://www.ncbi.nlm.nih.gov/pubmed/37654834
http://dx.doi.org/10.6026/97320630018938
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