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The use of Ephedra herbs in the treatment of COVID-19
OBJECTIVE: Ephedra herbs are the only extant genus in its family, Ephedraceae, and order, Ephedrales. It has been prescribed in traditional medicine for improving headaches and respiratory infections. On the other hand, because the coronavirus disease 2019 (COVID-19) causes respiratory problems and...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mashhad University of Medical Sciences
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465882/ https://www.ncbi.nlm.nih.gov/pubmed/37654998 http://dx.doi.org/10.22038/AJP.2022.21607 |
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author | Sadeghi Dousari, Amin Karimian Amroabadi, Marzieh Soofi Neyestani, Zahra Taati Moghadam, Majid Satarzadeh, Naghmeh |
author_facet | Sadeghi Dousari, Amin Karimian Amroabadi, Marzieh Soofi Neyestani, Zahra Taati Moghadam, Majid Satarzadeh, Naghmeh |
author_sort | Sadeghi Dousari, Amin |
collection | PubMed |
description | OBJECTIVE: Ephedra herbs are the only extant genus in its family, Ephedraceae, and order, Ephedrales. It has been prescribed in traditional medicine for improving headaches and respiratory infections. On the other hand, because the coronavirus disease 2019 (COVID-19) causes respiratory problems and COVID-19 pandemic is the most widespread outbreak that has affected humanity in the last century, the current review aims using literature search to investigate the effects of the Ephedra herbs compounds on COVID-19 to supply a reference for its clinical application in the inhibition and remedy of COVID-19. MATERIALS AND METHODS: This review was performed using articles published in various databases, including Web of Science, PubMed, Scopus, and Google Scholar, without a time limit. For this paper, the following keywords were used: "Ephedra", "coronavirus disease 2019", "COVID-19", "Severe acute respiratory syndrome coronavirus 2" or "SARS CoV 2". RESULTS: The results of this review show that the Ephedra herbs have effectiveness on COVID-19 and its compounds can bind to angiotensin-converting enzyme 2 (ACE2) with a high affinity and act as a blocker and prevent the binding of the virus. CONCLUSION: Some plants used in traditional medicine, including the Ephedra herbs, with their active compounds, can be considered a candidate with high potential for the control and prevention of COVID-19. |
format | Online Article Text |
id | pubmed-10465882 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Mashhad University of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-104658822023-08-31 The use of Ephedra herbs in the treatment of COVID-19 Sadeghi Dousari, Amin Karimian Amroabadi, Marzieh Soofi Neyestani, Zahra Taati Moghadam, Majid Satarzadeh, Naghmeh Avicenna J Phytomed Review Article OBJECTIVE: Ephedra herbs are the only extant genus in its family, Ephedraceae, and order, Ephedrales. It has been prescribed in traditional medicine for improving headaches and respiratory infections. On the other hand, because the coronavirus disease 2019 (COVID-19) causes respiratory problems and COVID-19 pandemic is the most widespread outbreak that has affected humanity in the last century, the current review aims using literature search to investigate the effects of the Ephedra herbs compounds on COVID-19 to supply a reference for its clinical application in the inhibition and remedy of COVID-19. MATERIALS AND METHODS: This review was performed using articles published in various databases, including Web of Science, PubMed, Scopus, and Google Scholar, without a time limit. For this paper, the following keywords were used: "Ephedra", "coronavirus disease 2019", "COVID-19", "Severe acute respiratory syndrome coronavirus 2" or "SARS CoV 2". RESULTS: The results of this review show that the Ephedra herbs have effectiveness on COVID-19 and its compounds can bind to angiotensin-converting enzyme 2 (ACE2) with a high affinity and act as a blocker and prevent the binding of the virus. CONCLUSION: Some plants used in traditional medicine, including the Ephedra herbs, with their active compounds, can be considered a candidate with high potential for the control and prevention of COVID-19. Mashhad University of Medical Sciences 2023 /pmc/articles/PMC10465882/ /pubmed/37654998 http://dx.doi.org/10.22038/AJP.2022.21607 Text en https://creativecommons.org/licenses/by/3.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/ (https://creativecommons.org/licenses/by/3.0/) ) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Sadeghi Dousari, Amin Karimian Amroabadi, Marzieh Soofi Neyestani, Zahra Taati Moghadam, Majid Satarzadeh, Naghmeh The use of Ephedra herbs in the treatment of COVID-19 |
title | The use of Ephedra herbs in the treatment of COVID-19 |
title_full | The use of Ephedra herbs in the treatment of COVID-19 |
title_fullStr | The use of Ephedra herbs in the treatment of COVID-19 |
title_full_unstemmed | The use of Ephedra herbs in the treatment of COVID-19 |
title_short | The use of Ephedra herbs in the treatment of COVID-19 |
title_sort | use of ephedra herbs in the treatment of covid-19 |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465882/ https://www.ncbi.nlm.nih.gov/pubmed/37654998 http://dx.doi.org/10.22038/AJP.2022.21607 |
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