Therapeutic HDAC inhibition in hypermutant diffuse intrinsic pontine glioma

Constitutional mismatch repair deficiency (CMMRD) is a cancer predisposition syndrome associated with the development of hypermutant pediatric high-grade glioma, and confers a poor prognosis. While therapeutic histone deacetylase (HDAC) inhibition of diffuse intrinsic pontine glioma (DIPG) has been...

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Detalles Bibliográficos
Autores principales: Noll, Alyssa, Myers, Carrie, Biery, Matthew C., Meechan, Michael, Tahiri, Sophie, Rajendran, Asmitha, Berens, Michael E., Paine, Danyelle, Byron, Sara, Zhang, Jiaming, Winter, Conrad, Pakiam, Fiona, Leary, Sarah E.S., Cole, Bonnie L., Jackson, Evangeline R., Dun, Matthew D., Foster, Jessica B., Evans, Myron K., Pattwell, Siobhan S., Olson, James M., Vitanza, Nicholas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465940/
https://www.ncbi.nlm.nih.gov/pubmed/37603953
http://dx.doi.org/10.1016/j.neo.2023.100921

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