Cargando…
Regulatory principles and mechanisms governing the onset of random X-chromosome inactivation
X-chromosome inactivation (XCI) has evolved in mammals to compensate for the difference in X-chromosomal dosage between the sexes. In placental mammals, XCI is initiated during early embryonic development through upregulation of the long noncoding RNA Xist from one randomly chosen X chromosome in ea...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465972/ https://www.ncbi.nlm.nih.gov/pubmed/37356341 http://dx.doi.org/10.1016/j.gde.2023.102063 |