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Regulatory principles and mechanisms governing the onset of random X-chromosome inactivation
X-chromosome inactivation (XCI) has evolved in mammals to compensate for the difference in X-chromosomal dosage between the sexes. In placental mammals, XCI is initiated during early embryonic development through upregulation of the long noncoding RNA Xist from one randomly chosen X chromosome in ea...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465972/ https://www.ncbi.nlm.nih.gov/pubmed/37356341 http://dx.doi.org/10.1016/j.gde.2023.102063 |