Bidirectional Mendelian Randomization and Multiphenotype GWAS Show Causality and Shared Pathophysiology Between Depression and Type 2 Diabetes

OBJECTIVE: Depression is a common comorbidity of type 2 diabetes. We assessed the causal relationships and shared genetics between them. RESEARCH DESIGN AND METHODS: We applied two-sample, bidirectional Mendelian randomization (MR) to assess causality between type 2 diabetes and depression. We inves...

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Detalles Bibliográficos
Autores principales: Maina, Jared G., Balkhiyarova, Zhanna, Nouwen, Arie, Pupko, Igor, Ulrich, Anna, Boissel, Mathilde, Bonnefond, Amélie, Froguel, Philippe, Khamis, Amna, Prokopenko, Inga, Kaakinen, Marika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465984/
https://www.ncbi.nlm.nih.gov/pubmed/37494602
http://dx.doi.org/10.2337/dc22-2373

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