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Inhibition of the interaction between Hippo/YAP and Akt signaling with ursolic acid and 3′3-diindolylmethane suppresses esophageal cancer tumorigenesis

Hippo/YAP signaling hinders cancer progression. Inactivation of this pathway contributes to the development of esophageal cancer by activation of Akt. However, the possible interaction between Akt and Hippo/YAP pathways in esophageal cancer progression is unclear. In this study, we found that ursoli...

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Detalles Bibliográficos
Autores principales: Meng, Ruo Yu, Li, Cong Shan, Hu, Dan, Kwon, Soon-Gu, Jin, Hua, Chai, Ok Hee, Lee, Ju-Seog, Kim, Soo Mi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10466072/
https://www.ncbi.nlm.nih.gov/pubmed/37641811
http://dx.doi.org/10.4196/kjpp.2023.27.5.493