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A Patient with Werner’s Syndrome Who Underwent Aortic Valve Replacement through Minimally Invasive Cardiac Surgery

Werner’s syndrome (WS) is a genetic disorder presenting with premature senility. In the present study, we performed minimally invasive cardiac surgery (MICS)-aortic valve replacement (AVR) on a patient with Werner’s syndrome who presented with aortic stenosis. The patient, a 49-year-old Japanese man...

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Autores principales: Sumiyoshi, Riki, Morita, Hideki, Kusadokoro, Sho, Fujii, Kento, Kawaura, Hiroyuki, Aoki, Masakazu, Nagano, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Editorial Committee of Annals of Thoracic and Cardiovascular Surgery 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10466116/
https://www.ncbi.nlm.nih.gov/pubmed/35264497
http://dx.doi.org/10.5761/atcs.cr.21-00214
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author Sumiyoshi, Riki
Morita, Hideki
Kusadokoro, Sho
Fujii, Kento
Kawaura, Hiroyuki
Aoki, Masakazu
Nagano, Hiroshi
author_facet Sumiyoshi, Riki
Morita, Hideki
Kusadokoro, Sho
Fujii, Kento
Kawaura, Hiroyuki
Aoki, Masakazu
Nagano, Hiroshi
author_sort Sumiyoshi, Riki
collection PubMed
description Werner’s syndrome (WS) is a genetic disorder presenting with premature senility. In the present study, we performed minimally invasive cardiac surgery (MICS)-aortic valve replacement (AVR) on a patient with Werner’s syndrome who presented with aortic stenosis. The patient, a 49-year-old Japanese man, was brought to the emergency room with dyspnea during exercise. On echocardiography, severe aortic stenosis was found and surgery was planned. He had poorly controlled diabetes mellitus and underwent MICS-AVR to avoid the risk of sternal osteomyelitis, which resulted in a good outcome. The aortic valve had sclerotic changes and a genetic disease was suspected based on the onset of aortic stenosis at a young age, characteristic appearance, and various signs of aging. Genetic testing led to the diagnosis of WS.
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spelling pubmed-104661162023-08-31 A Patient with Werner’s Syndrome Who Underwent Aortic Valve Replacement through Minimally Invasive Cardiac Surgery Sumiyoshi, Riki Morita, Hideki Kusadokoro, Sho Fujii, Kento Kawaura, Hiroyuki Aoki, Masakazu Nagano, Hiroshi Ann Thorac Cardiovasc Surg Case Report Werner’s syndrome (WS) is a genetic disorder presenting with premature senility. In the present study, we performed minimally invasive cardiac surgery (MICS)-aortic valve replacement (AVR) on a patient with Werner’s syndrome who presented with aortic stenosis. The patient, a 49-year-old Japanese man, was brought to the emergency room with dyspnea during exercise. On echocardiography, severe aortic stenosis was found and surgery was planned. He had poorly controlled diabetes mellitus and underwent MICS-AVR to avoid the risk of sternal osteomyelitis, which resulted in a good outcome. The aortic valve had sclerotic changes and a genetic disease was suspected based on the onset of aortic stenosis at a young age, characteristic appearance, and various signs of aging. Genetic testing led to the diagnosis of WS. The Editorial Committee of Annals of Thoracic and Cardiovascular Surgery 2022-03-10 2023 /pmc/articles/PMC10466116/ /pubmed/35264497 http://dx.doi.org/10.5761/atcs.cr.21-00214 Text en ©2023 Annals of Thoracic and Cardiovascular Surgery https://creativecommons.org/licenses/by-nc-nd/4.0/This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives International License (https://creativecommons.org/licenses/by-nc-nd/4.0/)
spellingShingle Case Report
Sumiyoshi, Riki
Morita, Hideki
Kusadokoro, Sho
Fujii, Kento
Kawaura, Hiroyuki
Aoki, Masakazu
Nagano, Hiroshi
A Patient with Werner’s Syndrome Who Underwent Aortic Valve Replacement through Minimally Invasive Cardiac Surgery
title A Patient with Werner’s Syndrome Who Underwent Aortic Valve Replacement through Minimally Invasive Cardiac Surgery
title_full A Patient with Werner’s Syndrome Who Underwent Aortic Valve Replacement through Minimally Invasive Cardiac Surgery
title_fullStr A Patient with Werner’s Syndrome Who Underwent Aortic Valve Replacement through Minimally Invasive Cardiac Surgery
title_full_unstemmed A Patient with Werner’s Syndrome Who Underwent Aortic Valve Replacement through Minimally Invasive Cardiac Surgery
title_short A Patient with Werner’s Syndrome Who Underwent Aortic Valve Replacement through Minimally Invasive Cardiac Surgery
title_sort patient with werner’s syndrome who underwent aortic valve replacement through minimally invasive cardiac surgery
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10466116/
https://www.ncbi.nlm.nih.gov/pubmed/35264497
http://dx.doi.org/10.5761/atcs.cr.21-00214
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