Pooled allogeneic faecal microbiota MaaT013 for steroid-resistant gastrointestinal acute graft-versus-host disease: a single-arm, multicentre phase 2 trial

BACKGROUND: Failure of gastrointestinal acute graft-versus-host disease (GI-aGvHD) to respond to steroid therapy is associated with limited further therapeutic options. We aimed to assess the safety and efficacy of the first-in-human use of the pooled allogeneic faecal microbiota, MaaT013, for the t...

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Detalles Bibliográficos
Autores principales: Malard, Florent, Loschi, Michael, Huynh, Anne, Cluzeau, Thomas, Guenounou, Sarah, Legrand, Faezeh, Magro, Leonardo, Orvain, Corentin, Charbonnier, Amandine, Panz-Klapuch, Marta, Desmier, Deborah, Mear, Jean-Baptiste, Cornillon, Jérôme, Robin, Christine, Daguindau, Etienne, Bilger, Karin, Vehreschild, Maria J.G.T., Chevallier, Patrice, Labussière-Wallet, Hélène, Mediavilla, Clémence, Couturier, Marie-Anne, Bulabois, Claude-Eric, Camus, Vincent, Chantepie, Sylvain, Ceballos, Patrice, Gaugler, Béatrice, Holler, Ernst, Doré, Joël, Prestat, Emmanuel, Gasc, Cyrielle, Plantamura, Emilie, Mohty, Mohamad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10466244/
https://www.ncbi.nlm.nih.gov/pubmed/37654670
http://dx.doi.org/10.1016/j.eclinm.2023.102111

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