A GPX4-targeted photosensitizer to reverse hypoxia-induced inhibition of ferroptosis for non-small cell lung cancer therapy

Ferroptosis therapy is gradually becoming a new strategy for the treatment of non-small cell lung cancer (NSCLC) because of its active iron metabolism. Because the hypoxic microenvironment in NSCLC inhibits ferroptosis heavily, the therapeutic effect of some ferroptosis inducers is severely limited....

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Detalles Bibliográficos
Autores principales: Hu, Qiao, Zhu, Wanjie, Du, Jianjun, Ge, Haoying, Zheng, Jiazhu, Long, Saran, Fan, Jiangli, Peng, Xiaojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10466276/
https://www.ncbi.nlm.nih.gov/pubmed/37655031
http://dx.doi.org/10.1039/d3sc01597a

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