Inactivation influences the extent of inhibition of voltage-gated Ca(+2) channels by Gem—implications for channelopathies

Voltage-gated Ca(2+) channels (VGCC) directly control muscle contraction and neurotransmitter release, and slower processes such as cell differentiation, migration, and death. They are potently inhibited by RGK GTP-ases (Rem, Rem2, Rad, and Gem/Kir), which decrease Ca(2+) channel membrane expression...

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Detalles Bibliográficos
Autores principales: Allam, Salma, Levenson-Palmer, Rose, Chia Chang, Zuleen, Kaur, Sukhjinder, Cernuda, Bryan, Raman, Ananya, Booth, Audrey, Dobbins, Scott, Suppa, Gabrielle, Yang, Jian, Buraei, Zafir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10466392/
https://www.ncbi.nlm.nih.gov/pubmed/37654674
http://dx.doi.org/10.3389/fphys.2023.1155976

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