The Application of Bio-orthogonality for In Vivo Animal Imaging

[Image: see text] The application of bio-orthogonality has greatly facilitated numerous aspects of biological studies in recent years. In particular, bio-orthogonal chemistry has transformed biological research, including in vitro conjugate chemistry, target identification, and biomedical imaging. I...

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Autores principales: Yang, Jun, Zhu, Biyue, Ran, Chongzhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nanjing University and American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10466453/
https://www.ncbi.nlm.nih.gov/pubmed/37655167
http://dx.doi.org/10.1021/cbmi.3c00033
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author Yang, Jun
Zhu, Biyue
Ran, Chongzhao
author_facet Yang, Jun
Zhu, Biyue
Ran, Chongzhao
author_sort Yang, Jun
collection PubMed
description [Image: see text] The application of bio-orthogonality has greatly facilitated numerous aspects of biological studies in recent years. In particular, bio-orthogonal chemistry has transformed biological research, including in vitro conjugate chemistry, target identification, and biomedical imaging. In this review, we highlighted examples of bio-orthogonal in vivo imaging published in recent years. We grouped the references into two major categories: bio-orthogonal chemistry-related imaging and in vivo imaging with bio-orthogonal nonconjugated pairing. Lastly, we discussed the challenges and opportunities of bio-orthogonality for in vivo imaging.
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spelling pubmed-104664532023-08-31 The Application of Bio-orthogonality for In Vivo Animal Imaging Yang, Jun Zhu, Biyue Ran, Chongzhao Chem Biomed Imaging [Image: see text] The application of bio-orthogonality has greatly facilitated numerous aspects of biological studies in recent years. In particular, bio-orthogonal chemistry has transformed biological research, including in vitro conjugate chemistry, target identification, and biomedical imaging. In this review, we highlighted examples of bio-orthogonal in vivo imaging published in recent years. We grouped the references into two major categories: bio-orthogonal chemistry-related imaging and in vivo imaging with bio-orthogonal nonconjugated pairing. Lastly, we discussed the challenges and opportunities of bio-orthogonality for in vivo imaging. Nanjing University and American Chemical Society 2023-07-07 /pmc/articles/PMC10466453/ /pubmed/37655167 http://dx.doi.org/10.1021/cbmi.3c00033 Text en © 2023 The Authors. Co-published by Nanjing University and American Chemical Society https://creativecommons.org/licenses/by-nc-nd/4.0/Permits non-commercial access and re-use, provided that author attribution and integrity are maintained; but does not permit creation of adaptations or other derivative works (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Yang, Jun
Zhu, Biyue
Ran, Chongzhao
The Application of Bio-orthogonality for In Vivo Animal Imaging
title The Application of Bio-orthogonality for In Vivo Animal Imaging
title_full The Application of Bio-orthogonality for In Vivo Animal Imaging
title_fullStr The Application of Bio-orthogonality for In Vivo Animal Imaging
title_full_unstemmed The Application of Bio-orthogonality for In Vivo Animal Imaging
title_short The Application of Bio-orthogonality for In Vivo Animal Imaging
title_sort application of bio-orthogonality for in vivo animal imaging
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10466453/
https://www.ncbi.nlm.nih.gov/pubmed/37655167
http://dx.doi.org/10.1021/cbmi.3c00033
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