Human cardiac organoids: A recent revolution in disease modeling and regenerative medicine

Three-dimensional (3D) myocardial tissues for studying human heart biology, physiology and pharmacology have recently received lots of attention. Organoids as 3D mini-organs are created from multiple cell types (i.e. induced pluripotent stem cells (iPSCs) or embryonic stem cells (ESCs)) with other s...

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Autores principales: Roshanravan, Neda, Ghaffari, Samad, Bastani, Sepideh, Pahlavan, Sara, Asghari, Samira, Doustvandi, Mohammad Amin, Jalilzadeh- Razin, Sepideh, Dastouri, Mohammadreza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tabriz University of Medical Sciences 2023
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10466470/
https://www.ncbi.nlm.nih.gov/pubmed/37654821
http://dx.doi.org/10.34172/jcvtr.2023.31830
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author Roshanravan, Neda
Ghaffari, Samad
Bastani, Sepideh
Pahlavan, Sara
Asghari, Samira
Doustvandi, Mohammad Amin
Jalilzadeh- Razin, Sepideh
Dastouri, Mohammadreza
author_facet Roshanravan, Neda
Ghaffari, Samad
Bastani, Sepideh
Pahlavan, Sara
Asghari, Samira
Doustvandi, Mohammad Amin
Jalilzadeh- Razin, Sepideh
Dastouri, Mohammadreza
author_sort Roshanravan, Neda
collection PubMed
description Three-dimensional (3D) myocardial tissues for studying human heart biology, physiology and pharmacology have recently received lots of attention. Organoids as 3D mini-organs are created from multiple cell types (i.e. induced pluripotent stem cells (iPSCs) or embryonic stem cells (ESCs)) with other supporting co-cultured cells such as endothelial cells or fibroblasts. Cardiac organoid culture technologies are bringing about significant advances in organ research and allows for the establishment of tissue regeneration and disease modeling. The present review provides an overview of the recent advances in human cardiac organoid platforms in disease biology and for cardiovascular regenerative medicine.
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spelling pubmed-104664702023-08-31 Human cardiac organoids: A recent revolution in disease modeling and regenerative medicine Roshanravan, Neda Ghaffari, Samad Bastani, Sepideh Pahlavan, Sara Asghari, Samira Doustvandi, Mohammad Amin Jalilzadeh- Razin, Sepideh Dastouri, Mohammadreza J Cardiovasc Thorac Res Review Article Three-dimensional (3D) myocardial tissues for studying human heart biology, physiology and pharmacology have recently received lots of attention. Organoids as 3D mini-organs are created from multiple cell types (i.e. induced pluripotent stem cells (iPSCs) or embryonic stem cells (ESCs)) with other supporting co-cultured cells such as endothelial cells or fibroblasts. Cardiac organoid culture technologies are bringing about significant advances in organ research and allows for the establishment of tissue regeneration and disease modeling. The present review provides an overview of the recent advances in human cardiac organoid platforms in disease biology and for cardiovascular regenerative medicine. Tabriz University of Medical Sciences 2023 2023-06-29 /pmc/articles/PMC10466470/ /pubmed/37654821 http://dx.doi.org/10.34172/jcvtr.2023.31830 Text en © 2023 The Author(s) https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Roshanravan, Neda
Ghaffari, Samad
Bastani, Sepideh
Pahlavan, Sara
Asghari, Samira
Doustvandi, Mohammad Amin
Jalilzadeh- Razin, Sepideh
Dastouri, Mohammadreza
Human cardiac organoids: A recent revolution in disease modeling and regenerative medicine
title Human cardiac organoids: A recent revolution in disease modeling and regenerative medicine
title_full Human cardiac organoids: A recent revolution in disease modeling and regenerative medicine
title_fullStr Human cardiac organoids: A recent revolution in disease modeling and regenerative medicine
title_full_unstemmed Human cardiac organoids: A recent revolution in disease modeling and regenerative medicine
title_short Human cardiac organoids: A recent revolution in disease modeling and regenerative medicine
title_sort human cardiac organoids: a recent revolution in disease modeling and regenerative medicine
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10466470/
https://www.ncbi.nlm.nih.gov/pubmed/37654821
http://dx.doi.org/10.34172/jcvtr.2023.31830
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