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Evaluation of the Brain Stem Auditory Evoked Potential Response among New Borns Post-Recovery after Hyper-Bilirubinemia: An Original Research

INTRODUCTION: Neurological harm from neonatal hyperbilirubinemia includes loss of hearing and encephalopathy. The current research used the “Brainstem Evoked Response Audiometry (BERA)” test to screen for as well as assess hearing loss in newborns who had recovered from hyperbilirubinemia. MATERIALS...

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Autores principales: Dolma, Kunzes, Thekkethil, Jathin Sam, Paul, Anish G., Rao, P. Srinivas Narasinga, Parikh, Taral, Somaraj, Vinej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10466513/
https://www.ncbi.nlm.nih.gov/pubmed/37654294
http://dx.doi.org/10.4103/jpbs.jpbs_476_22
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author Dolma, Kunzes
Thekkethil, Jathin Sam
Paul, Anish G.
Rao, P. Srinivas Narasinga
Parikh, Taral
Somaraj, Vinej
author_facet Dolma, Kunzes
Thekkethil, Jathin Sam
Paul, Anish G.
Rao, P. Srinivas Narasinga
Parikh, Taral
Somaraj, Vinej
author_sort Dolma, Kunzes
collection PubMed
description INTRODUCTION: Neurological harm from neonatal hyperbilirubinemia includes loss of hearing and encephalopathy. The current research used the “Brainstem Evoked Response Audiometry (BERA)” test to screen for as well as assess hearing loss in newborns who had recovered from hyperbilirubinemia. MATERIALS AND PROCEDURES: A cross-sectional comparative investigation was conducted at a tertiary care center. Fifty neonates were included out of which 25 were healthy and 25 received treatment for the increased bilirubin. Prior to BERA testing, the subjects’ ears were examined for any obstruction. Following a conventional lab procedure described, the BERA recordings were carried out after the neonate fell asleep on its own. The data collected were compared for the significance using the ANOVA, keeping P < 0.05 as significant. RESULTS: In comparison to the controls, a large proportion of neonates in cases had BERA wave latencies that were delayed (I-R = 80, L = 84; III- R = 76, L = 84; V- R = 84, L = 88 percentages latencies). The percentage of subjects in whom the latencies was noted for the healthy neonates was lesser than the case group (I-R = 8, L = 24; III- R = 8, L = 8; V- R = 4, L = 12 percentages latencies). Comparable numbers of infants in each group had inter-peak latencies that were lengthy. Subjects in the case group showed that the threshold hearing as per the WHO grade was mild (R = 32, L = 36) and moderate (R = 32, L = 28). CONCLUSION: Elevated serum bilirubin may cause damage to hearing capability. After hyperbilirubinemia has been completely treated, BERA can detect even the slightest degree of hearing damage. BERA is therefore a useful technique for the quick recognition of hearing impairment in newborns. Early treatment helps in the prognosis so that the neurosensory systems can fully mature, and the patient can lead a quality life.
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spelling pubmed-104665132023-08-31 Evaluation of the Brain Stem Auditory Evoked Potential Response among New Borns Post-Recovery after Hyper-Bilirubinemia: An Original Research Dolma, Kunzes Thekkethil, Jathin Sam Paul, Anish G. Rao, P. Srinivas Narasinga Parikh, Taral Somaraj, Vinej J Pharm Bioallied Sci Original Article INTRODUCTION: Neurological harm from neonatal hyperbilirubinemia includes loss of hearing and encephalopathy. The current research used the “Brainstem Evoked Response Audiometry (BERA)” test to screen for as well as assess hearing loss in newborns who had recovered from hyperbilirubinemia. MATERIALS AND PROCEDURES: A cross-sectional comparative investigation was conducted at a tertiary care center. Fifty neonates were included out of which 25 were healthy and 25 received treatment for the increased bilirubin. Prior to BERA testing, the subjects’ ears were examined for any obstruction. Following a conventional lab procedure described, the BERA recordings were carried out after the neonate fell asleep on its own. The data collected were compared for the significance using the ANOVA, keeping P < 0.05 as significant. RESULTS: In comparison to the controls, a large proportion of neonates in cases had BERA wave latencies that were delayed (I-R = 80, L = 84; III- R = 76, L = 84; V- R = 84, L = 88 percentages latencies). The percentage of subjects in whom the latencies was noted for the healthy neonates was lesser than the case group (I-R = 8, L = 24; III- R = 8, L = 8; V- R = 4, L = 12 percentages latencies). Comparable numbers of infants in each group had inter-peak latencies that were lengthy. Subjects in the case group showed that the threshold hearing as per the WHO grade was mild (R = 32, L = 36) and moderate (R = 32, L = 28). CONCLUSION: Elevated serum bilirubin may cause damage to hearing capability. After hyperbilirubinemia has been completely treated, BERA can detect even the slightest degree of hearing damage. BERA is therefore a useful technique for the quick recognition of hearing impairment in newborns. Early treatment helps in the prognosis so that the neurosensory systems can fully mature, and the patient can lead a quality life. Wolters Kluwer - Medknow 2023-07 2023-07-05 /pmc/articles/PMC10466513/ /pubmed/37654294 http://dx.doi.org/10.4103/jpbs.jpbs_476_22 Text en Copyright: © 2023 Journal of Pharmacy and Bioallied Sciences https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Dolma, Kunzes
Thekkethil, Jathin Sam
Paul, Anish G.
Rao, P. Srinivas Narasinga
Parikh, Taral
Somaraj, Vinej
Evaluation of the Brain Stem Auditory Evoked Potential Response among New Borns Post-Recovery after Hyper-Bilirubinemia: An Original Research
title Evaluation of the Brain Stem Auditory Evoked Potential Response among New Borns Post-Recovery after Hyper-Bilirubinemia: An Original Research
title_full Evaluation of the Brain Stem Auditory Evoked Potential Response among New Borns Post-Recovery after Hyper-Bilirubinemia: An Original Research
title_fullStr Evaluation of the Brain Stem Auditory Evoked Potential Response among New Borns Post-Recovery after Hyper-Bilirubinemia: An Original Research
title_full_unstemmed Evaluation of the Brain Stem Auditory Evoked Potential Response among New Borns Post-Recovery after Hyper-Bilirubinemia: An Original Research
title_short Evaluation of the Brain Stem Auditory Evoked Potential Response among New Borns Post-Recovery after Hyper-Bilirubinemia: An Original Research
title_sort evaluation of the brain stem auditory evoked potential response among new borns post-recovery after hyper-bilirubinemia: an original research
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10466513/
https://www.ncbi.nlm.nih.gov/pubmed/37654294
http://dx.doi.org/10.4103/jpbs.jpbs_476_22
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