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To Assess the Serum and Salivary Biomarkers in People with and Without Diabetes

The study was conducted to assess the serum and salivary biomarkers in people with and without diabetes. Among the 100 participants in this cross-sectional comparative study, 59 men and 61 women aged 32 to 59 years old were randomly assigned to category I (consisting of 50 diabetes mellitus (DM) pat...

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Autores principales: Sidhu, Gagandeep K., Sidhu, Sandeep, Singh, Harkanwal P., Gandhi, Piyush, Sidhu, Jaskirat, Kathuria, Navneet S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10466568/
https://www.ncbi.nlm.nih.gov/pubmed/37654399
http://dx.doi.org/10.4103/jpbs.jpbs_415_22
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author Sidhu, Gagandeep K.
Sidhu, Sandeep
Singh, Harkanwal P.
Gandhi, Piyush
Sidhu, Jaskirat
Kathuria, Navneet S.
author_facet Sidhu, Gagandeep K.
Sidhu, Sandeep
Singh, Harkanwal P.
Gandhi, Piyush
Sidhu, Jaskirat
Kathuria, Navneet S.
author_sort Sidhu, Gagandeep K.
collection PubMed
description The study was conducted to assess the serum and salivary biomarkers in people with and without diabetes. Among the 100 participants in this cross-sectional comparative study, 59 men and 61 women aged 32 to 59 years old were randomly assigned to category I (consisting of 50 diabetes mellitus (DM) patients of both types 1 and 2) or category II (consisting of 50 healthy volunteers) to serve as comparisons. Since there is no difference in the amounts of salivary biomarkers across the various types of diabetes, they are all grouped together. Several biochemical indicators were measured by measuring the amounts in the participants’ saliva and serum samples. There was little to no difference between the two categories when comparing saliva and serum levels. Although there was a strong correlation between serum and salivary glucose, amylase, total proteins, albumin, and globulin levels in DM patients, there was also a strong correlation between diabetics and non-diabetics for these same markers.
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spelling pubmed-104665682023-08-31 To Assess the Serum and Salivary Biomarkers in People with and Without Diabetes Sidhu, Gagandeep K. Sidhu, Sandeep Singh, Harkanwal P. Gandhi, Piyush Sidhu, Jaskirat Kathuria, Navneet S. J Pharm Bioallied Sci Original Article The study was conducted to assess the serum and salivary biomarkers in people with and without diabetes. Among the 100 participants in this cross-sectional comparative study, 59 men and 61 women aged 32 to 59 years old were randomly assigned to category I (consisting of 50 diabetes mellitus (DM) patients of both types 1 and 2) or category II (consisting of 50 healthy volunteers) to serve as comparisons. Since there is no difference in the amounts of salivary biomarkers across the various types of diabetes, they are all grouped together. Several biochemical indicators were measured by measuring the amounts in the participants’ saliva and serum samples. There was little to no difference between the two categories when comparing saliva and serum levels. Although there was a strong correlation between serum and salivary glucose, amylase, total proteins, albumin, and globulin levels in DM patients, there was also a strong correlation between diabetics and non-diabetics for these same markers. Wolters Kluwer - Medknow 2023-07 2023-07-05 /pmc/articles/PMC10466568/ /pubmed/37654399 http://dx.doi.org/10.4103/jpbs.jpbs_415_22 Text en Copyright: © 2023 Journal of Pharmacy and Bioallied Sciences https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Sidhu, Gagandeep K.
Sidhu, Sandeep
Singh, Harkanwal P.
Gandhi, Piyush
Sidhu, Jaskirat
Kathuria, Navneet S.
To Assess the Serum and Salivary Biomarkers in People with and Without Diabetes
title To Assess the Serum and Salivary Biomarkers in People with and Without Diabetes
title_full To Assess the Serum and Salivary Biomarkers in People with and Without Diabetes
title_fullStr To Assess the Serum and Salivary Biomarkers in People with and Without Diabetes
title_full_unstemmed To Assess the Serum and Salivary Biomarkers in People with and Without Diabetes
title_short To Assess the Serum and Salivary Biomarkers in People with and Without Diabetes
title_sort to assess the serum and salivary biomarkers in people with and without diabetes
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10466568/
https://www.ncbi.nlm.nih.gov/pubmed/37654399
http://dx.doi.org/10.4103/jpbs.jpbs_415_22
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