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Evaluation of the Remineralisation of the Demineralized Enamel Surrounding Orthodontic Brackets using the Nano Hydroxyapatite: An Original Study

INTRODUCTION: The orthodontic appliances have been known to accelerate enamel loss due to various reasons. Since there are few studies supporting the role of the nano-HAP in the mineralization of the demineralized tooth surfaces, the current study compared nano-HAP’s capacity to remineralize the dem...

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Autores principales: Samineni, Sahithi, Rathore, Bhupendra S., Rohilla, Nitika, Varma, Praveen K., Niwlikar, Kumar B., Sarma, Sankar N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10466584/
https://www.ncbi.nlm.nih.gov/pubmed/37654328
http://dx.doi.org/10.4103/jpbs.jpbs_447_22
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author Samineni, Sahithi
Rathore, Bhupendra S.
Rohilla, Nitika
Varma, Praveen K.
Niwlikar, Kumar B.
Sarma, Sankar N.
author_facet Samineni, Sahithi
Rathore, Bhupendra S.
Rohilla, Nitika
Varma, Praveen K.
Niwlikar, Kumar B.
Sarma, Sankar N.
author_sort Samineni, Sahithi
collection PubMed
description INTRODUCTION: The orthodontic appliances have been known to accelerate enamel loss due to various reasons. Since there are few studies supporting the role of the nano-HAP in the mineralization of the demineralized tooth surfaces, the current study compared nano-HAP’s capacity to remineralize the demineralized enamel layer surrounding braces at various concentration levels. MATERIALS AND PROCEDURES: This investigation involved 60 healthy permanent premolars that had just been excised. All specimens had 3M-Unitek brackets glued to their buccal surfaces. The samples were artificially demineralized and divided into three groups. The control group, Toothpaste ApaCare, and ApaCareTM varnish. Before and after remineralization, selected samples from each group were analyzed using a “Scanning Electron Microscope (SEM)” and evaluated using “Energy Dispersive X-Ray Analysis (EDAX).” Spectrometer and profilometer were used for the study of surface and the color. Statistics were used to analyze the outcomes. The threshold for significance was fixed at 0.05. RESULTS: After remineralization by nano-HAP, there was a significant rise (P < 0.001) in both calcium and phosphorus levels. This was picked up by EDAX, and SEM verified it. When compared to the control group, the nano-HAP application greatly improved the color measurements in the study groups (P < 0.001), and it also resulted in a significant decrease in surface roughness (P < 0.001). CONCLUSION: Our study’s results showed that nano-HAP could be successful in restoring demineralized enamel around brackets, reducing the surface roughness and color of the enamel surface.
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spelling pubmed-104665842023-08-31 Evaluation of the Remineralisation of the Demineralized Enamel Surrounding Orthodontic Brackets using the Nano Hydroxyapatite: An Original Study Samineni, Sahithi Rathore, Bhupendra S. Rohilla, Nitika Varma, Praveen K. Niwlikar, Kumar B. Sarma, Sankar N. J Pharm Bioallied Sci Original Article INTRODUCTION: The orthodontic appliances have been known to accelerate enamel loss due to various reasons. Since there are few studies supporting the role of the nano-HAP in the mineralization of the demineralized tooth surfaces, the current study compared nano-HAP’s capacity to remineralize the demineralized enamel layer surrounding braces at various concentration levels. MATERIALS AND PROCEDURES: This investigation involved 60 healthy permanent premolars that had just been excised. All specimens had 3M-Unitek brackets glued to their buccal surfaces. The samples were artificially demineralized and divided into three groups. The control group, Toothpaste ApaCare, and ApaCareTM varnish. Before and after remineralization, selected samples from each group were analyzed using a “Scanning Electron Microscope (SEM)” and evaluated using “Energy Dispersive X-Ray Analysis (EDAX).” Spectrometer and profilometer were used for the study of surface and the color. Statistics were used to analyze the outcomes. The threshold for significance was fixed at 0.05. RESULTS: After remineralization by nano-HAP, there was a significant rise (P < 0.001) in both calcium and phosphorus levels. This was picked up by EDAX, and SEM verified it. When compared to the control group, the nano-HAP application greatly improved the color measurements in the study groups (P < 0.001), and it also resulted in a significant decrease in surface roughness (P < 0.001). CONCLUSION: Our study’s results showed that nano-HAP could be successful in restoring demineralized enamel around brackets, reducing the surface roughness and color of the enamel surface. Wolters Kluwer - Medknow 2023-07 2023-07-05 /pmc/articles/PMC10466584/ /pubmed/37654328 http://dx.doi.org/10.4103/jpbs.jpbs_447_22 Text en Copyright: © 2023 Journal of Pharmacy and Bioallied Sciences https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Samineni, Sahithi
Rathore, Bhupendra S.
Rohilla, Nitika
Varma, Praveen K.
Niwlikar, Kumar B.
Sarma, Sankar N.
Evaluation of the Remineralisation of the Demineralized Enamel Surrounding Orthodontic Brackets using the Nano Hydroxyapatite: An Original Study
title Evaluation of the Remineralisation of the Demineralized Enamel Surrounding Orthodontic Brackets using the Nano Hydroxyapatite: An Original Study
title_full Evaluation of the Remineralisation of the Demineralized Enamel Surrounding Orthodontic Brackets using the Nano Hydroxyapatite: An Original Study
title_fullStr Evaluation of the Remineralisation of the Demineralized Enamel Surrounding Orthodontic Brackets using the Nano Hydroxyapatite: An Original Study
title_full_unstemmed Evaluation of the Remineralisation of the Demineralized Enamel Surrounding Orthodontic Brackets using the Nano Hydroxyapatite: An Original Study
title_short Evaluation of the Remineralisation of the Demineralized Enamel Surrounding Orthodontic Brackets using the Nano Hydroxyapatite: An Original Study
title_sort evaluation of the remineralisation of the demineralized enamel surrounding orthodontic brackets using the nano hydroxyapatite: an original study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10466584/
https://www.ncbi.nlm.nih.gov/pubmed/37654328
http://dx.doi.org/10.4103/jpbs.jpbs_447_22
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