Cargando…

Avascular Necrosis of the Hip after the COVID-19 Pandemic

BACKGROUND AND OBJECTIVES: It is clear that COVID-19 can have a wide range of effects on the body, and the musculoskeletal system is no exception. Studies are ongoing to better understand how the virus may impact the hip bone and joint tissue. However, it is known that COVID-19 can cause inflammatio...

Descripción completa

Detalles Bibliográficos
Autores principales: Sinha, Priti R., Mallick, Nitin, Sahu, Ramjee L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10466589/
https://www.ncbi.nlm.nih.gov/pubmed/37654323
http://dx.doi.org/10.4103/jpbs.jpbs_87_23
_version_ 1785098918774702080
author Sinha, Priti R.
Mallick, Nitin
Sahu, Ramjee L.
author_facet Sinha, Priti R.
Mallick, Nitin
Sahu, Ramjee L.
author_sort Sinha, Priti R.
collection PubMed
description BACKGROUND AND OBJECTIVES: It is clear that COVID-19 can have a wide range of effects on the body, and the musculoskeletal system is no exception. Studies are ongoing to better understand how the virus may impact the hip bone and joint tissue. However, it is known that COVID-19 can cause inflammation and damage to various parts of the body, including the bones and joints, which could lead to pain, stiffness, and other symptoms. MATERIALS AND METHODS: A retrospective analysis is done with ten patients admitted to the hospital due to COVID-19 and later complained of hip pain. Magnetic resonance imaging (MRI) was performed on the patients, and it was found that they had degenerative changes characterized by avascular necrosis (AVN) of the head of the femur. One of the patients had a history of previous surgery on the femur with a plate and screws and was doing well but developed AVN after contracting COVID-19. RESULTS: Observation among these groups shows a strong association between the history of COVID-19, high levels of IgG antibodies, the presence of joint abnormalities, and moderately severe symptoms. There is no evidence of identifying autoimmune, degenerative, or AVN diseases. This set of patients responded positively to supportive therapy and anti-inflammatory drugs used in empirical treatment, which subsided joint pain and acute inflammatory symptoms. CONCLUSIONS: It has been determined that there are significant musculoskeletal complications in COVID-19 patients, including AVN, which may be caused by the high use of steroids and microembolism leading to bone necrosis. Therefore, further studies and long-term follow-up are recommended.
format Online
Article
Text
id pubmed-10466589
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Wolters Kluwer - Medknow
record_format MEDLINE/PubMed
spelling pubmed-104665892023-08-31 Avascular Necrosis of the Hip after the COVID-19 Pandemic Sinha, Priti R. Mallick, Nitin Sahu, Ramjee L. J Pharm Bioallied Sci Original Article BACKGROUND AND OBJECTIVES: It is clear that COVID-19 can have a wide range of effects on the body, and the musculoskeletal system is no exception. Studies are ongoing to better understand how the virus may impact the hip bone and joint tissue. However, it is known that COVID-19 can cause inflammation and damage to various parts of the body, including the bones and joints, which could lead to pain, stiffness, and other symptoms. MATERIALS AND METHODS: A retrospective analysis is done with ten patients admitted to the hospital due to COVID-19 and later complained of hip pain. Magnetic resonance imaging (MRI) was performed on the patients, and it was found that they had degenerative changes characterized by avascular necrosis (AVN) of the head of the femur. One of the patients had a history of previous surgery on the femur with a plate and screws and was doing well but developed AVN after contracting COVID-19. RESULTS: Observation among these groups shows a strong association between the history of COVID-19, high levels of IgG antibodies, the presence of joint abnormalities, and moderately severe symptoms. There is no evidence of identifying autoimmune, degenerative, or AVN diseases. This set of patients responded positively to supportive therapy and anti-inflammatory drugs used in empirical treatment, which subsided joint pain and acute inflammatory symptoms. CONCLUSIONS: It has been determined that there are significant musculoskeletal complications in COVID-19 patients, including AVN, which may be caused by the high use of steroids and microembolism leading to bone necrosis. Therefore, further studies and long-term follow-up are recommended. Wolters Kluwer - Medknow 2023-07 2023-07-05 /pmc/articles/PMC10466589/ /pubmed/37654323 http://dx.doi.org/10.4103/jpbs.jpbs_87_23 Text en Copyright: © 2023 Journal of Pharmacy and Bioallied Sciences https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Sinha, Priti R.
Mallick, Nitin
Sahu, Ramjee L.
Avascular Necrosis of the Hip after the COVID-19 Pandemic
title Avascular Necrosis of the Hip after the COVID-19 Pandemic
title_full Avascular Necrosis of the Hip after the COVID-19 Pandemic
title_fullStr Avascular Necrosis of the Hip after the COVID-19 Pandemic
title_full_unstemmed Avascular Necrosis of the Hip after the COVID-19 Pandemic
title_short Avascular Necrosis of the Hip after the COVID-19 Pandemic
title_sort avascular necrosis of the hip after the covid-19 pandemic
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10466589/
https://www.ncbi.nlm.nih.gov/pubmed/37654323
http://dx.doi.org/10.4103/jpbs.jpbs_87_23
work_keys_str_mv AT sinhapritir avascularnecrosisofthehipafterthecovid19pandemic
AT mallicknitin avascularnecrosisofthehipafterthecovid19pandemic
AT sahuramjeel avascularnecrosisofthehipafterthecovid19pandemic