Cargando…

Assessment of Pain Management After Orthognathic Surgery by the Administration of Montelukast: An Original Research

INTRODUCTION: Opioid may cause undue risk after surgical procedures like orthognathic surgeries. The present study was aimed to determine how the preoperative administration of oral montelukast affected the degree of postoperative discomfort following bimaxillary orthognathic surgery (BOS). METHODOL...

Descripción completa

Detalles Bibliográficos
Autores principales: Kumar, G. Jeevan, Mansuri, Samir, Nizar, Sarin A., Rehman, Sameera Qureshi Mohd, Kumar, Abhishekh, Baig, Fawaz Abdul Hamid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10466630/
https://www.ncbi.nlm.nih.gov/pubmed/37654356
http://dx.doi.org/10.4103/jpbs.jpbs_432_22
_version_ 1785098928657530880
author Kumar, G. Jeevan
Mansuri, Samir
Nizar, Sarin A.
Rehman, Sameera Qureshi Mohd
Kumar, Abhishekh
Baig, Fawaz Abdul Hamid
author_facet Kumar, G. Jeevan
Mansuri, Samir
Nizar, Sarin A.
Rehman, Sameera Qureshi Mohd
Kumar, Abhishekh
Baig, Fawaz Abdul Hamid
author_sort Kumar, G. Jeevan
collection PubMed
description INTRODUCTION: Opioid may cause undue risk after surgical procedures like orthognathic surgeries. The present study was aimed to determine how the preoperative administration of oral montelukast affected the degree of postoperative discomfort following bimaxillary orthognathic surgery (BOS). METHODOLOGY: This study included all skeletal class III subjects scheduled for BOS. The participants were split into placebo and montelukast groups at random. Every patient received a 10-mL serving of apple juice an hour prior to the surgery; however, for the intervention group, a montelukast 10 mg pill was dissolved in the juice. The same surgical team and general anesthetic guidelines were used for all procedures. The visual analog scale (VAS) was used to calculate postoperative pain at designated intervals. The significance level for the statistical analysis was determined using the Statistical Package for the Social Sciences (SPSS) version 23. RESULTS: The control subjects had a higher level of pain at all the intervals than the intended drug test group. Also, the control group needed more analgesics than the test group. There was one observation made that the length of the surgery had an impact on the postoperative pain. CONCLUSION: Preoperative montelukast medication may be useful in minimizing postoperative discomfort following bimaxillary orthognathic surgery. More research is required for greater relevance.
format Online
Article
Text
id pubmed-10466630
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Wolters Kluwer - Medknow
record_format MEDLINE/PubMed
spelling pubmed-104666302023-08-31 Assessment of Pain Management After Orthognathic Surgery by the Administration of Montelukast: An Original Research Kumar, G. Jeevan Mansuri, Samir Nizar, Sarin A. Rehman, Sameera Qureshi Mohd Kumar, Abhishekh Baig, Fawaz Abdul Hamid J Pharm Bioallied Sci Original Article INTRODUCTION: Opioid may cause undue risk after surgical procedures like orthognathic surgeries. The present study was aimed to determine how the preoperative administration of oral montelukast affected the degree of postoperative discomfort following bimaxillary orthognathic surgery (BOS). METHODOLOGY: This study included all skeletal class III subjects scheduled for BOS. The participants were split into placebo and montelukast groups at random. Every patient received a 10-mL serving of apple juice an hour prior to the surgery; however, for the intervention group, a montelukast 10 mg pill was dissolved in the juice. The same surgical team and general anesthetic guidelines were used for all procedures. The visual analog scale (VAS) was used to calculate postoperative pain at designated intervals. The significance level for the statistical analysis was determined using the Statistical Package for the Social Sciences (SPSS) version 23. RESULTS: The control subjects had a higher level of pain at all the intervals than the intended drug test group. Also, the control group needed more analgesics than the test group. There was one observation made that the length of the surgery had an impact on the postoperative pain. CONCLUSION: Preoperative montelukast medication may be useful in minimizing postoperative discomfort following bimaxillary orthognathic surgery. More research is required for greater relevance. Wolters Kluwer - Medknow 2023-07 2023-07-05 /pmc/articles/PMC10466630/ /pubmed/37654356 http://dx.doi.org/10.4103/jpbs.jpbs_432_22 Text en Copyright: © 2023 Journal of Pharmacy and Bioallied Sciences https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Kumar, G. Jeevan
Mansuri, Samir
Nizar, Sarin A.
Rehman, Sameera Qureshi Mohd
Kumar, Abhishekh
Baig, Fawaz Abdul Hamid
Assessment of Pain Management After Orthognathic Surgery by the Administration of Montelukast: An Original Research
title Assessment of Pain Management After Orthognathic Surgery by the Administration of Montelukast: An Original Research
title_full Assessment of Pain Management After Orthognathic Surgery by the Administration of Montelukast: An Original Research
title_fullStr Assessment of Pain Management After Orthognathic Surgery by the Administration of Montelukast: An Original Research
title_full_unstemmed Assessment of Pain Management After Orthognathic Surgery by the Administration of Montelukast: An Original Research
title_short Assessment of Pain Management After Orthognathic Surgery by the Administration of Montelukast: An Original Research
title_sort assessment of pain management after orthognathic surgery by the administration of montelukast: an original research
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10466630/
https://www.ncbi.nlm.nih.gov/pubmed/37654356
http://dx.doi.org/10.4103/jpbs.jpbs_432_22
work_keys_str_mv AT kumargjeevan assessmentofpainmanagementafterorthognathicsurgerybytheadministrationofmontelukastanoriginalresearch
AT mansurisamir assessmentofpainmanagementafterorthognathicsurgerybytheadministrationofmontelukastanoriginalresearch
AT nizarsarina assessmentofpainmanagementafterorthognathicsurgerybytheadministrationofmontelukastanoriginalresearch
AT rehmansameeraqureshimohd assessmentofpainmanagementafterorthognathicsurgerybytheadministrationofmontelukastanoriginalresearch
AT kumarabhishekh assessmentofpainmanagementafterorthognathicsurgerybytheadministrationofmontelukastanoriginalresearch
AT baigfawazabdulhamid assessmentofpainmanagementafterorthognathicsurgerybytheadministrationofmontelukastanoriginalresearch