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Assessment of Pain Management After Orthognathic Surgery by the Administration of Montelukast: An Original Research
INTRODUCTION: Opioid may cause undue risk after surgical procedures like orthognathic surgeries. The present study was aimed to determine how the preoperative administration of oral montelukast affected the degree of postoperative discomfort following bimaxillary orthognathic surgery (BOS). METHODOL...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10466630/ https://www.ncbi.nlm.nih.gov/pubmed/37654356 http://dx.doi.org/10.4103/jpbs.jpbs_432_22 |
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author | Kumar, G. Jeevan Mansuri, Samir Nizar, Sarin A. Rehman, Sameera Qureshi Mohd Kumar, Abhishekh Baig, Fawaz Abdul Hamid |
author_facet | Kumar, G. Jeevan Mansuri, Samir Nizar, Sarin A. Rehman, Sameera Qureshi Mohd Kumar, Abhishekh Baig, Fawaz Abdul Hamid |
author_sort | Kumar, G. Jeevan |
collection | PubMed |
description | INTRODUCTION: Opioid may cause undue risk after surgical procedures like orthognathic surgeries. The present study was aimed to determine how the preoperative administration of oral montelukast affected the degree of postoperative discomfort following bimaxillary orthognathic surgery (BOS). METHODOLOGY: This study included all skeletal class III subjects scheduled for BOS. The participants were split into placebo and montelukast groups at random. Every patient received a 10-mL serving of apple juice an hour prior to the surgery; however, for the intervention group, a montelukast 10 mg pill was dissolved in the juice. The same surgical team and general anesthetic guidelines were used for all procedures. The visual analog scale (VAS) was used to calculate postoperative pain at designated intervals. The significance level for the statistical analysis was determined using the Statistical Package for the Social Sciences (SPSS) version 23. RESULTS: The control subjects had a higher level of pain at all the intervals than the intended drug test group. Also, the control group needed more analgesics than the test group. There was one observation made that the length of the surgery had an impact on the postoperative pain. CONCLUSION: Preoperative montelukast medication may be useful in minimizing postoperative discomfort following bimaxillary orthognathic surgery. More research is required for greater relevance. |
format | Online Article Text |
id | pubmed-10466630 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-104666302023-08-31 Assessment of Pain Management After Orthognathic Surgery by the Administration of Montelukast: An Original Research Kumar, G. Jeevan Mansuri, Samir Nizar, Sarin A. Rehman, Sameera Qureshi Mohd Kumar, Abhishekh Baig, Fawaz Abdul Hamid J Pharm Bioallied Sci Original Article INTRODUCTION: Opioid may cause undue risk after surgical procedures like orthognathic surgeries. The present study was aimed to determine how the preoperative administration of oral montelukast affected the degree of postoperative discomfort following bimaxillary orthognathic surgery (BOS). METHODOLOGY: This study included all skeletal class III subjects scheduled for BOS. The participants were split into placebo and montelukast groups at random. Every patient received a 10-mL serving of apple juice an hour prior to the surgery; however, for the intervention group, a montelukast 10 mg pill was dissolved in the juice. The same surgical team and general anesthetic guidelines were used for all procedures. The visual analog scale (VAS) was used to calculate postoperative pain at designated intervals. The significance level for the statistical analysis was determined using the Statistical Package for the Social Sciences (SPSS) version 23. RESULTS: The control subjects had a higher level of pain at all the intervals than the intended drug test group. Also, the control group needed more analgesics than the test group. There was one observation made that the length of the surgery had an impact on the postoperative pain. CONCLUSION: Preoperative montelukast medication may be useful in minimizing postoperative discomfort following bimaxillary orthognathic surgery. More research is required for greater relevance. Wolters Kluwer - Medknow 2023-07 2023-07-05 /pmc/articles/PMC10466630/ /pubmed/37654356 http://dx.doi.org/10.4103/jpbs.jpbs_432_22 Text en Copyright: © 2023 Journal of Pharmacy and Bioallied Sciences https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Kumar, G. Jeevan Mansuri, Samir Nizar, Sarin A. Rehman, Sameera Qureshi Mohd Kumar, Abhishekh Baig, Fawaz Abdul Hamid Assessment of Pain Management After Orthognathic Surgery by the Administration of Montelukast: An Original Research |
title | Assessment of Pain Management After Orthognathic Surgery by the Administration of Montelukast: An Original Research |
title_full | Assessment of Pain Management After Orthognathic Surgery by the Administration of Montelukast: An Original Research |
title_fullStr | Assessment of Pain Management After Orthognathic Surgery by the Administration of Montelukast: An Original Research |
title_full_unstemmed | Assessment of Pain Management After Orthognathic Surgery by the Administration of Montelukast: An Original Research |
title_short | Assessment of Pain Management After Orthognathic Surgery by the Administration of Montelukast: An Original Research |
title_sort | assessment of pain management after orthognathic surgery by the administration of montelukast: an original research |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10466630/ https://www.ncbi.nlm.nih.gov/pubmed/37654356 http://dx.doi.org/10.4103/jpbs.jpbs_432_22 |
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