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Several dementia subtypes and mild cognitive impairment share brain reduction of neurotransmitter precursor amino acids, impaired energy metabolism, and lipid hyperoxidation

OBJECTIVE: Dementias and mild cognitive impairment (MCI) are associated with variously combined changes in the neurotransmitter system and signaling, from neurotransmitter synthesis to synaptic binding. The study tested the hypothesis that different dementia subtypes and MCI may share similar reduct...

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Detalles Bibliográficos
Autores principales: Aquilani, Roberto, Cotta Ramusino, Matteo, Maestri, Roberto, Iadarola, Paolo, Boselli, Mirella, Perini, Giulia, Boschi, Federica, Dossena, Maurizia, Bellini, Anna, Buonocore, Daniela, Doria, Enrico, Costa, Alfredo, Verri, Manuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10466813/
https://www.ncbi.nlm.nih.gov/pubmed/37655338
http://dx.doi.org/10.3389/fnagi.2023.1237469