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Quantitative proteomic and phosphoproteomic analysis reveal the relationship between mitochondrial dysfunction and cytoskeletal remodeling in hiPSC-CMs deficient in PINK1

BACKGROUND: Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) are seed cells that can be used for alternative treatment of myocardial damage. However, their immaturity limits their clinical application. Mitochondrial development accompanies cardiomyocyte maturation, and PINK1 pl...

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Detalles Bibliográficos
Autores principales:	Liu, Huiwen, Wang, Li, Xu, Hao, Tan, Bin, Yi, Qin, Deng, Hongrong, Chen, Yunxia, He, Bolin, Tian, Jie, Zhu, Jing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10466879/ https://www.ncbi.nlm.nih.gov/pubmed/37649075 http://dx.doi.org/10.1186/s12967-023-04467-y

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