Stochastic epithelial-mesenchymal transitions diversify non-cancerous lung cell behaviours

Epithelial-mesenchymal plasticity (EMP) is a hallmark of cancer. By enabling cells to shift between different morphological and functional states, EMP promotes invasion, metastasis and therapy resistance. We report that near-diploid non-cancerous human epithelial lung cells spontaneously shift along...

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Detalles Bibliográficos
Autores principales: Bhatia, Sugandha, Gunter, Jennifer H, Burgess, Joshua T, Adams, Mark N, O'Byrne, Kenneth, Thompson, Erik W, Duijf, Pascal HG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2023
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10466920/
https://www.ncbi.nlm.nih.gov/pubmed/37611490
http://dx.doi.org/10.1016/j.tranon.2023.101760

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