Cargando…

The Future of AI in Ovarian Cancer Research: The Large Language Models Perspective

Conversational large language model (LLM)-based chatbots utilize neural networks to process natural language. By generating highly sophisticated outputs from contextual input text, they revolutionize the access to further learning, leading to the development of new skills and personalized interactio...

Descripción completa

Detalles Bibliográficos
Autores principales: Laios, Alexandros, Theophilou, Georgios, De Jong, Diederick, Kalampokis, Evangelos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10467259/
https://www.ncbi.nlm.nih.gov/pubmed/37624621
http://dx.doi.org/10.1177/10732748231197915
_version_ 1785099076713316352
author Laios, Alexandros
Theophilou, Georgios
De Jong, Diederick
Kalampokis, Evangelos
author_facet Laios, Alexandros
Theophilou, Georgios
De Jong, Diederick
Kalampokis, Evangelos
author_sort Laios, Alexandros
collection PubMed
description Conversational large language model (LLM)-based chatbots utilize neural networks to process natural language. By generating highly sophisticated outputs from contextual input text, they revolutionize the access to further learning, leading to the development of new skills and personalized interactions. Although they are not developed to provide healthcare, their potential to address biomedical issues is rather unexplored. Healthcare digitalization and documentation of electronic health records is now developing into a standard practice. Developing tools to facilitate clinical review of unstructured data such as LLMs can derive clinical meaningful insights for ovarian cancer, a heterogeneous but devastating disease. Compared to standard approaches, they can host capacity to condense results and optimize analysis time. To help accelerate research in biomedical language processing and improve the validity of scientific writing, task-specific and domain-specific language models may be required. In turn, we propose a bespoke, proprietary ovarian cancer-specific natural language using solely in-domain text, whereas transfer learning drifts away from the pretrained language models to fine-tune task-specific models for all possible downstream applications. This venture will be fueled by the abundance of unstructured text information in the electronic health records resulting in ovarian cancer research ultimately reaching its linguistic home.
format Online
Article
Text
id pubmed-10467259
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher SAGE Publications
record_format MEDLINE/PubMed
spelling pubmed-104672592023-08-31 The Future of AI in Ovarian Cancer Research: The Large Language Models Perspective Laios, Alexandros Theophilou, Georgios De Jong, Diederick Kalampokis, Evangelos Cancer Control An Inventory of Epithelial Ovarian Cancer Targets: “Evidence-based” Options-Editorial Conversational large language model (LLM)-based chatbots utilize neural networks to process natural language. By generating highly sophisticated outputs from contextual input text, they revolutionize the access to further learning, leading to the development of new skills and personalized interactions. Although they are not developed to provide healthcare, their potential to address biomedical issues is rather unexplored. Healthcare digitalization and documentation of electronic health records is now developing into a standard practice. Developing tools to facilitate clinical review of unstructured data such as LLMs can derive clinical meaningful insights for ovarian cancer, a heterogeneous but devastating disease. Compared to standard approaches, they can host capacity to condense results and optimize analysis time. To help accelerate research in biomedical language processing and improve the validity of scientific writing, task-specific and domain-specific language models may be required. In turn, we propose a bespoke, proprietary ovarian cancer-specific natural language using solely in-domain text, whereas transfer learning drifts away from the pretrained language models to fine-tune task-specific models for all possible downstream applications. This venture will be fueled by the abundance of unstructured text information in the electronic health records resulting in ovarian cancer research ultimately reaching its linguistic home. SAGE Publications 2023-08-25 /pmc/articles/PMC10467259/ /pubmed/37624621 http://dx.doi.org/10.1177/10732748231197915 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle An Inventory of Epithelial Ovarian Cancer Targets: “Evidence-based” Options-Editorial
Laios, Alexandros
Theophilou, Georgios
De Jong, Diederick
Kalampokis, Evangelos
The Future of AI in Ovarian Cancer Research: The Large Language Models Perspective
title The Future of AI in Ovarian Cancer Research: The Large Language Models Perspective
title_full The Future of AI in Ovarian Cancer Research: The Large Language Models Perspective
title_fullStr The Future of AI in Ovarian Cancer Research: The Large Language Models Perspective
title_full_unstemmed The Future of AI in Ovarian Cancer Research: The Large Language Models Perspective
title_short The Future of AI in Ovarian Cancer Research: The Large Language Models Perspective
title_sort future of ai in ovarian cancer research: the large language models perspective
topic An Inventory of Epithelial Ovarian Cancer Targets: “Evidence-based” Options-Editorial
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10467259/
https://www.ncbi.nlm.nih.gov/pubmed/37624621
http://dx.doi.org/10.1177/10732748231197915
work_keys_str_mv AT laiosalexandros thefutureofaiinovariancancerresearchthelargelanguagemodelsperspective
AT theophilougeorgios thefutureofaiinovariancancerresearchthelargelanguagemodelsperspective
AT dejongdiederick thefutureofaiinovariancancerresearchthelargelanguagemodelsperspective
AT kalampokisevangelos thefutureofaiinovariancancerresearchthelargelanguagemodelsperspective
AT laiosalexandros futureofaiinovariancancerresearchthelargelanguagemodelsperspective
AT theophilougeorgios futureofaiinovariancancerresearchthelargelanguagemodelsperspective
AT dejongdiederick futureofaiinovariancancerresearchthelargelanguagemodelsperspective
AT kalampokisevangelos futureofaiinovariancancerresearchthelargelanguagemodelsperspective